Frequency of night eating syndrome and melatonin levels in the urine of adolescents

IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL
T. Sorokman, L. Khlunovska
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引用次数: 0

Abstract

Aim. The aim is to study the frequency of night eating syndrome (NES) and its correlation with melatonin levels in the daily urine of adolescents. Materials and methods. Primary screening of 486 adolescents (15–18 years) with complaints of eating disorders, overweight, obesity, which included a survey (test “Depressive Disorders in Adolescents”, Night Eating Questionnaire (NEQ), Dutch Eating Behaviour Questionnaire (DEBQ) and anthropometry (BMI) was conducted. In the second stage, a sample of 56 adolescents (11.5 %) who met the NES criteria of DSM-5 (main group) and 50 adolescents who did not have NES (comparison group) was formed. The urine concentration of 6-sulfatoxymelatonin (6-COMT) was determined by enzyme immunoassay (Buhlmann 6-Sulfatoxymelatonin ELISA Kit, Switzerland). Results. Deficit of body weight had 3 (8.8 %) of adolescent boys, 20 (58.8 %) were overweight, 1 (2.9 %) – obese and only 10 (29.4 %) had the average normative values of body weight; among female adolescents, 1 (4.5 %) – body weight deficit and obesity, 10 (45.5 %) – overweight and average normative indicators. According to the DEBQ, restrictive eating behaviors were identified in 15 (26.8 %) adolescents; in 30 (53.6 %) adolescents – emotional and in 11 (19.6 %) adolescents – external. The mean score of the NEQ was 28.4 ± 2.2 and positively correlated with BMI (r = +0.62, P < 0.05). Participants who exceeded the screening threshold for NES (n = 56, 11.5 %) had increased BMI (P < 0.01), likelihood of overweight/obesity (P = 0.001), consumption of sugary drinks (P < 0.001), daytime sleep less than twice a week (P < 0.01), shorter sleep duration (P < 0.01), high and moderate levels of depression, lower levels of melatonin, which were inversely correlated with the results of the NEQ (r = -0.68, P < 0.05). Conclusions. The prevalence of NES among teenagers was 11.5 %. Among the types of eating behavior, the most common was the emotional type (53.6 %). Adolescents with NES had a significantly higher total depression score (96.7 ± 8.06, P < 0.001) and a lower level of 6-COMT (22.89 ± 3.44, P < 0.001), which was inversely correlated with the degree of NES (r = -0.68, P < 0.05), BMI (r = -0.74; P < 0.01) and depression level (r = -0.65; P < 0.01).
青少年夜间进食综合征频率与尿中褪黑素水平的关系
的目标。目的是研究夜间进食综合征(NES)的频率及其与青少年日尿中褪黑激素水平的相关性。材料和方法。对486名(15-18岁)抱怨饮食失调、超重、肥胖的青少年进行了初步筛查,其中包括调查(测试“青少年抑郁症”)、夜间饮食问卷(NEQ)、荷兰饮食行为问卷(DEBQ)和人体测量(BMI)。第二阶段,选取符合DSM-5中NES标准的青少年56人(11.5%)(主组)和不具有NES的青少年50人(对照组)。采用酶免疫法(Buhlmann 6-sulfatoxymelatonin ELISA Kit,瑞士)测定尿中6-sulfatoxymelatonin (6-COMT)的浓度。青春期男孩体重不足3例(8.8%),超重20例(58.8%),轻度肥胖1例(2.9%),平均体重正常值10例(29.4%);在女性青少年中,1人(4.5%)——体重不足和肥胖,10人(45.5%)——超重和平均规范指标。根据DEBQ, 15名(26.8%)青少年有限制性饮食行为;30名(53.6%)青少年有情绪性,11名(19.6%)青少年有情绪性。NEQ平均评分为28.4±2.2,与BMI呈正相关(r = +0.62, P < 0.05)。超过NES筛查阈值的参与者(n = 56, 11.5%) BMI升高(P < 0.01),超重/肥胖可能性(P = 0.001),含糖饮料摄入量(P < 0.001),每周白天睡眠少于两次(P < 0.01),睡眠时间较短(P < 0.01),重度和中度抑郁,褪黑激素水平较低,这些与NEQ结果呈负相关(r = -0.68, P < 0.05)。青少年中NES的患病率为11.5%。在饮食行为的类型中,最常见的是情绪性(53.6%)。青少年抑郁总分(96.7±8.06,P < 0.001)显著高于抑郁总分(96.7±8.06,P < 0.001), 6-COMT显著低于抑郁总分(22.89±3.44,P < 0.001),且抑郁总分与抑郁程度(r = -0.68, P < 0.05)、体重指数(r = -0.74;P < 0.01)和抑郁程度(r = -0.65;P < 0.01)。
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来源期刊
Zaporozhye Medical Journal
Zaporozhye Medical Journal MEDICINE, GENERAL & INTERNAL-
自引率
0.00%
发文量
72
审稿时长
8 weeks
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