Soft Liner with antimicrobial activity

Simone Kreve, C. L. Vidal, O. L. Alves, A. Reis
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引用次数: 1

Abstract

Objective: To develop a material for denture relining and assess the microbiological and mechanical properties. The proposed liner was obtained through the incorporation of nanostructured silver vanadate (AgVO3) at 0, 1, 2.5, 5, and 10% polyethyl methacrylate (PEMA) containing plasticizer. Methods: Antimicrobial efficacy was evaluated by the Kirby Bauer agar method against Enterococcus faecalis, Pseudomonas aeruginosa, Candida albicans and Staphyloccocus aureus (n = 5); and mechanical properties were also assessed through roughness, such as Shore A hardness and tensile test. The results were analyzed by ANOVA and Tukey’s Multiple Comparison test (α = 0.05). Results: The material with AgVO3 at concentrations of 1% and 2.5% showed antimicrobial activity for E. faecalis, and 5% and 10% groups were effective for E. faecalis, P. aeruginosa and C. albicans. In the 5% group, hardness remained unchanged (p 0.05). Conclusion: Obtaining the material with antimicrobial potential promoted efficacy against E. faecalis, P. aeruginosa and C. albicans, kept the roughness property unchanged, did not change the adhesion property of the material to polymethyl methacrylate, and it maintained the hardness values compatible with resilient denture liners.
具有抗菌活性的软衬
目的:研制一种义齿内衬材料,并对其微生物学和力学性能进行评价。通过掺入纳米结构钒酸银(AgVO3)在0、1、2.5、5和10%含增塑剂的聚甲基丙烯酸酯(PEMA)中得到所提出的内衬。方法:采用Kirby Bauer琼脂法对5株粪肠球菌、铜绿假单胞菌、白色念珠菌和金黄色葡萄球菌进行抑菌效果评价;并通过粗糙度,如邵氏硬度和拉伸试验来评估机械性能。采用方差分析和Tukey多重比较检验(α = 0.05)对结果进行分析。结果:AgVO3浓度为1%和2.5%的材料对粪肠球菌均有抑菌活性,5%和10%组对粪肠球菌、铜绿假单胞菌和白色念珠菌均有抑菌效果。5%组硬度不变(p < 0.05)。结论:获得具有抗菌潜力的材料,可以提高对粪肠杆菌、铜绿假单胞菌和白色念珠菌的抗菌效果,保持材料的粗糙度不变,不改变材料与聚甲基丙烯酸甲酯的粘附性能,并保持与弹性义齿衬套相匹配的硬度值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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