Colorectal Carcinoma with Metastasis to Oral Mucosa; Two Cases Report

Abstract

Oral metastasis of tumours is known to cause 1% of all oral malignancies and is most often the result of a primary in lung, breast and kidney [1,2]. The location of the metastasis is usually the jaw bones as opposed to soft tissues. A metastasis from colorectal adenocarcinoma to the soft tissues is hence extremely infrequent. The gingivae (55%) followed by the tongue (30%) are the most common soft tissue sites affected by metastatic tumour in the mouth [3]. The diagnosis of such cases is dependent on adequate history taking and although has a poor prognosis but early detection and effective treatment are necessary to aid in treatment and follow up. Here we report two cases of colorectal adenocarcinoma that metastasized to the oral gingiva and were diagnosed by histology and supportive immunohistochemistry.