Hydration: the review of 3 trials

D. Ivanov, M. Ivanova
{"title":"Hydration: the review of 3 trials","authors":"D. Ivanov, M. Ivanova","doi":"10.22141/2307-1257.9.1.2020.196911","DOIUrl":null,"url":null,"abstract":". The concepts of forced hydration and excessive forced hydration are discussed in the article. The authors emphasize that excessive forced hydration has a proven track record in improving the quality of life for dehydrated people. In case of normovolemia, there is no evidence of quality improvement and prolongation of life when excessive forced hydration is used. The issue of forced hydration in chronic kidney disease (CKD) is considered separately. Three randomized clinical trials were analyzed in which patients with CKD stage 1–2, 3 and 4–5 received forced hydration. The results of studies indicate the possible efficacy of forced hydration in stage 1–2 CKD in patients with normal or increased renal functional reserve. In stage 3 CKD, forced hydration showed no benefits, and in stage 4–5 CKD, it resulted in greater renal function loss. Summarizing these data, the authors concluded that it is probably appropriate for healthy people to consume the amount of fluid that provides physiological diuresis of 1.2–1.8 L and normal urine osmolarity. Forced hydration is often excessive, excessive forced hydration may not promote a healthy lifestyle. Forced hydration becomes excessive forced hydration as kidney function decreases. Possibly, the benefits of forced hydration are lost in CKD with progression of renal function loss. The effect of forced hydration for 12 months may be positive in stage 1 CKD and stage 2 CKD with normal renal functional reserve. Forced hydration is probably inexpedient in chronic stages 3–5.","PeriodicalId":17874,"journal":{"name":"KIDNEYS","volume":"284 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"KIDNEYS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22141/2307-1257.9.1.2020.196911","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3

Abstract

. The concepts of forced hydration and excessive forced hydration are discussed in the article. The authors emphasize that excessive forced hydration has a proven track record in improving the quality of life for dehydrated people. In case of normovolemia, there is no evidence of quality improvement and prolongation of life when excessive forced hydration is used. The issue of forced hydration in chronic kidney disease (CKD) is considered separately. Three randomized clinical trials were analyzed in which patients with CKD stage 1–2, 3 and 4–5 received forced hydration. The results of studies indicate the possible efficacy of forced hydration in stage 1–2 CKD in patients with normal or increased renal functional reserve. In stage 3 CKD, forced hydration showed no benefits, and in stage 4–5 CKD, it resulted in greater renal function loss. Summarizing these data, the authors concluded that it is probably appropriate for healthy people to consume the amount of fluid that provides physiological diuresis of 1.2–1.8 L and normal urine osmolarity. Forced hydration is often excessive, excessive forced hydration may not promote a healthy lifestyle. Forced hydration becomes excessive forced hydration as kidney function decreases. Possibly, the benefits of forced hydration are lost in CKD with progression of renal function loss. The effect of forced hydration for 12 months may be positive in stage 1 CKD and stage 2 CKD with normal renal functional reserve. Forced hydration is probably inexpedient in chronic stages 3–5.
水合作用:3个试验的综述
. 本文讨论了强制水化和过度强制水化的概念。作者强调,过度的强制补水在改善脱水人群的生活质量方面有良好的记录。在正常血容量的情况下,没有证据表明当过度强制水合使用时,质量改善和寿命延长。慢性肾脏疾病(CKD)的强制水合问题是单独考虑的。我们分析了3个随机临床试验,其中CKD 1 - 2,3和4-5期患者接受了强制补水。研究结果表明,在肾功能储备正常或增加的1-2期CKD患者中,强制水化可能有效。在3期CKD中,强制水化没有任何益处,而在4-5期CKD中,它会导致更大的肾功能丧失。总结这些数据,作者得出结论,对于健康的人来说,饮用能够提供生理利尿的液体量为1.2-1.8升,尿液渗透压正常可能是合适的。强迫补水往往是过度的,过度的强迫补水可能不利于健康的生活方式。当肾功能下降时,强迫水合变成过度的强迫水合。随着肾功能丧失的进展,慢性肾病患者可能丧失了强制水合作用的益处。在肾功能储备正常的1期和2期CKD中,12个月的强制水合作用可能是阳性的。在慢性3-5期,强制补水可能是不合适的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信