Behavioral, Demographic, and Clinical determinants of HIV Status in Zambian Women

D. Gebreyohannes, J. Shen, K. Sams
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Abstract

The rate of human immunodeficiency virus (HIV) infection shows a diminishing trend globally while increasing in intensity of mortality, morbidity, and burden of HIV in Sub-Saharan Africa. The intertwined behavioral, demographic, and clinical determinants fueled the incidence of infections in Zambian women. This study aimed to determine the association between demographic, behavioral, and clinical determinants with HIV serostatus in Zambian women. With the conceptual framework of the World Health Organization Commission for Social Determinants of Health (CSDH) and the quantitative method of MANOVA, this study examined Zambian Demographic Health Survey data for Zambian women of two ages groups (adolescent and adult). The findings showed statistically significant results in the association between HIV serostatus and self-perceived HIV risk for both groups and in the association between education and HIV serostatus among women in both groups. However, there was no statistically significant association between behavioral, demographic, and clinical determinants of HIV serostatus. These findings imply the need to conduct prospective studies on such determinants to curb HIV and improve women community health in Africa. Keywords HIV serostatus; determinants of HIV serostatus, Self-perceived HIV risk, Zambia
行为,人口统计和临床决定因素在赞比亚妇女艾滋病毒状况
人类免疫缺陷病毒(艾滋病毒)感染率在全球呈下降趋势,而在撒哈拉以南非洲,艾滋病毒的死亡率、发病率和负担都在增加。行为、人口统计和临床决定因素交织在一起,助长了赞比亚妇女感染的发生率。本研究旨在确定赞比亚妇女的人口统计学、行为和临床决定因素与HIV血清状态之间的关系。利用世界卫生组织健康问题社会决定因素委员会(CSDH)的概念框架和方差分析(MANOVA)的定量方法,本研究检查了赞比亚两个年龄组(青少年和成人)妇女的人口健康调查数据。研究结果显示,在两组中,艾滋病毒血清状态与自我感知的艾滋病毒风险之间的关联以及两组中妇女的教育程度与艾滋病毒血清状态之间的关联具有统计学意义。然而,行为、人口统计学和HIV血清状态的临床决定因素之间没有统计学上的显著关联。这些发现意味着需要对这些决定因素进行前瞻性研究,以遏制艾滋病毒并改善非洲妇女社区健康。HIV;血清状态;艾滋病毒血清状态的决定因素,自我感知的艾滋病毒风险,赞比亚
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