Synchronous lung carcinomas of different histology within the same lobe

Andrew D. Cochrane FRACS , Peter L. Wallis FRCPA , Michael Mullerworth FRACS
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Abstract

Synchronous carcinomas were found at thoracotomy. Both tumours were within the same lobe of the lung but of different histology. There was a central squamous carcinoma with bronchial involvement and a peripheral adenocarcinoma but no evidence of lymph node or distant spread. This is an uncommon but probably under-reported finding. The literature suggests that the long-term prognosis in the documented cases of synchronous lung carcinoma is no worse than after resection of a single malignant lesion. The finding of 2 lesions on preoperative investigation or at operation does not necessarily indicate that the tumours are inoperable and should not preclude successful resection in selected patients.

同一肺叶内不同组织学的同步型肺癌
在开胸术中发现同步癌。两个肿瘤都在同一肺叶内,但组织学不同。有一例浸润支气管的中央鳞状癌和一例周围腺癌,但没有淋巴结或远处扩散的证据。这是一个不常见但可能被低估的发现。文献提示,有文献记载的同时性肺癌的长期预后并不比单个恶性病灶切除后的预后差。术前检查或手术中发现2个病变并不一定表明肿瘤不能手术,也不应排除某些患者成功切除。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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