Evaluation of Estrogen Receptor α and ß Genes Expression in Normal and Neoplastic Mammary Gland in Dogs by Real-time PCR

Q4 Pharmacology, Toxicology and Pharmaceutics

Current Pharmacogenomics and Personalized Medicine Pub Date : 2018-05-31 DOI:10.2174/1875692116666180907100151

M. Nassiri, Seyedeh Arezoo Hosseini, S. Ghovvati, M. Zabetian

引用次数: 1

Abstract

Mammary gland tumors are known to be among the commonest of neoplasms in humans as well as dogs. About 52% of all tumors correspond to mammary neoplasia, which is repeatedly reported among dogs and is the most common malignant neoplasia among bitches [1, 2]. Malignant tumors can be found in roughly 50% of mammary tumors in canids [2-4]. Malignant tumors are hormone-dependent neoplasms and might reappear after surgical removal or spread to other organs such as liver, lymph nodes, and lungs [5, 6].

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Real-time PCR法评价犬正常乳腺和肿瘤乳腺中雌激素受体α和ß基因的表达

众所周知，乳腺肿瘤是人类和狗中最常见的肿瘤之一。约52%的肿瘤对应乳腺肿瘤，在犬类中有反复报道，是母狗中最常见的恶性肿瘤[1,2]。犬科动物乳腺肿瘤中恶性肿瘤约占50%[2-4]。恶性肿瘤是激素依赖性肿瘤，手术切除后可能复发或扩散到肝、淋巴结、肺等其他器官[5,6]。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Pharmacogenomics and Personalized Medicine Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

0.40

自引率

0.00%

发文量

期刊介绍： Current Pharmacogenomics and Personalized Medicine (Formerly ‘Current Pharmacogenomics’) Current Pharmacogenomics and Personalized Medicine (CPPM) is an international peer reviewed biomedical journal that publishes expert reviews, and state of the art analyses on all aspects of pharmacogenomics and personalized medicine under a single cover. The CPPM addresses the complex transdisciplinary challenges and promises emerging from the fusion of knowledge domains in therapeutics and diagnostics (i.e., theragnostics). The journal bears in mind the increasingly globalized nature of health research and services.