Epidemiological Characteristics of Tick-Borne Encephalitis in the Sverdlovsk District over a 20-Year Period

N. Kolyasnikova, L. Chistyakova, A. V. Ponomareva, A. E. Platonov, V. V. Romanenko, А. Ishmukhametov, V. Akimkin
{"title":"Epidemiological Characteristics of Tick-Borne Encephalitis in the Sverdlovsk District over a 20-Year Period","authors":"N. Kolyasnikova, L. Chistyakova, A. V. Ponomareva, A. E. Platonov, V. V. Romanenko, А. Ishmukhametov, V. Akimkin","doi":"10.31631/2073-3046-2023-22-2-37-46","DOIUrl":null,"url":null,"abstract":"Relevance. Despite the ongoing program of mass vaccination of tick-borne encephalitis (TBE) for more than 20 years in the Sverdlovsk district, the incidence rate of TBE continues to exceed the average in Russia and the Ural Federal region.Aim. To analyze the main indicators of the manifestation of the epidemic process of TBE in the territory of the Sverdlovsk district under the conditions of planned vaccination over a 20-year period (2002–2021).Materials and methods. The article uses data from federal and regional statistical observations, reporting materials of the Department of Rospotrebnadzor in the Sverdlovsk district for 2002-2021, methods of statistical analysis.Results and discussion. During the study period (2002-2021), 3861 cases of TBE were registered in the Sverdlovsk district, while the highest incidence rate was detected in 2005 – 10.1 per 100 thousand population, and the lowest in 2020 – 1.0 per 100 thousand population. The share of the vector-borne mechanism was 78.4%, the unidentified path – 20.1%, alimentary – 1.5%. Analysis of the seasonal distribution of cases of TBE showed that the incidence is recorded from April to November. Cases of TBE were recorded in all age groups, including the child population. Most often, people aged 60 years old and older (24.6%) were ill with TBE. Among the children's population, the largest share fell on children aged 7–14 years (5.4%). Men of working age prevailed among the patients (66.0%). TBE was mainly registered among the unvaccinated population (81.5%) with a predominance of urban (86.1%). Officials predominated among the sick persons – 29.8%, pensioners made up 22.3%, unemployed – 19.8%. Persons whose work is professionally connected with the forest made up only 0.6%. The ongoing program of mass vaccination of TBE has led to a decrease in the proportion of severe and moderate forms of diseases (focal – 9.8% and meningeal – 24.0%) and an increase in the proportion of febrile (33.8%) and atypical forms (32.4%). Deaths during the studied period were recorded mainly among the adult unvaccinated population.Conclusions. The Sverdlovsk district continues to be a tense natural focus of TBE with a constantly recorded incidence among contingents of different age and social groups. In the absence of highly effective etiotropic drugs for the treatment of TBE, the only strategy for reducing the incidence of TBE, the development of severe forms and deaths in the territory of the Sverdlovsk district is mass vaccination of the population.","PeriodicalId":11736,"journal":{"name":"Epidemiology and Vaccinal Prevention","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Epidemiology and Vaccinal Prevention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31631/2073-3046-2023-22-2-37-46","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Relevance. Despite the ongoing program of mass vaccination of tick-borne encephalitis (TBE) for more than 20 years in the Sverdlovsk district, the incidence rate of TBE continues to exceed the average in Russia and the Ural Federal region.Aim. To analyze the main indicators of the manifestation of the epidemic process of TBE in the territory of the Sverdlovsk district under the conditions of planned vaccination over a 20-year period (2002–2021).Materials and methods. The article uses data from federal and regional statistical observations, reporting materials of the Department of Rospotrebnadzor in the Sverdlovsk district for 2002-2021, methods of statistical analysis.Results and discussion. During the study period (2002-2021), 3861 cases of TBE were registered in the Sverdlovsk district, while the highest incidence rate was detected in 2005 – 10.1 per 100 thousand population, and the lowest in 2020 – 1.0 per 100 thousand population. The share of the vector-borne mechanism was 78.4%, the unidentified path – 20.1%, alimentary – 1.5%. Analysis of the seasonal distribution of cases of TBE showed that the incidence is recorded from April to November. Cases of TBE were recorded in all age groups, including the child population. Most often, people aged 60 years old and older (24.6%) were ill with TBE. Among the children's population, the largest share fell on children aged 7–14 years (5.4%). Men of working age prevailed among the patients (66.0%). TBE was mainly registered among the unvaccinated population (81.5%) with a predominance of urban (86.1%). Officials predominated among the sick persons – 29.8%, pensioners made up 22.3%, unemployed – 19.8%. Persons whose work is professionally connected with the forest made up only 0.6%. The ongoing program of mass vaccination of TBE has led to a decrease in the proportion of severe and moderate forms of diseases (focal – 9.8% and meningeal – 24.0%) and an increase in the proportion of febrile (33.8%) and atypical forms (32.4%). Deaths during the studied period were recorded mainly among the adult unvaccinated population.Conclusions. The Sverdlovsk district continues to be a tense natural focus of TBE with a constantly recorded incidence among contingents of different age and social groups. In the absence of highly effective etiotropic drugs for the treatment of TBE, the only strategy for reducing the incidence of TBE, the development of severe forms and deaths in the territory of the Sverdlovsk district is mass vaccination of the population.
斯维尔德洛夫斯克地区20年来蜱传脑炎的流行病学特征
的相关性。尽管斯维尔德洛夫斯克地区20多年来一直在进行大规模接种蜱传脑炎(TBE)的计划,但TBE的发病率继续超过俄罗斯和乌拉尔联邦区的平均水平。在20年(2002-2021年)计划接种疫苗的情况下,分析斯维尔德洛夫斯克州境内乙脑流行过程表现的主要指标。材料和方法。本文使用的数据来自联邦和地区统计观察,2002-2021年斯维尔德洛夫斯克地区Rospotrebnadzor部门的报告材料,统计分析方法。结果和讨论。在研究期间(2002-2021年),斯维尔德洛夫斯克地区登记了3861例TBE病例,2005年发现的发病率最高,为每10万人10.1例,2020年最低,为每10万人1.0例。病媒传播机制占78.4%,途径不明占20.1%,消化道感染占1.5%。对TBE病例的季节分布分析表明,发病时间为4 - 11月。在包括儿童在内的所有年龄组中都记录了TBE病例。最常见的是60岁及以上的人(24.6%)患有TBE。在儿童人口中,7-14岁的儿童所占比例最大(5.4%)。患者中以工作年龄男性为主(66.0%)。TBE主要发生在未接种疫苗人群中(81.5%),以城市人群为主(86.1%)。官员在病人中占主导地位,占29.8%,养老金领取者占22.3%,失业者占19.8%。从事与森林有关的专业工作的人数仅占0.6%。正在进行的流行性脑炎大规模疫苗接种计划已导致严重和中度形式的疾病比例下降(局灶性- 9.8%,脑膜- 24.0%),发热形式(33.8%)和非典型形式(32.4%)的比例增加。研究期间的死亡主要发生在未接种疫苗的成年人群中。斯维尔德洛夫斯克地区仍然是俄罗斯联邦的一个紧张的自然焦点,不同年龄和社会群体的特遣队不断记录发病率。在缺乏治疗TBE的高效致病性药物的情况下,在斯维尔德洛夫斯克州境内减少TBE发病率、严重形式的发展和死亡的唯一战略是大规模接种人口疫苗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信