Pre-operative lipid profile of cardiac surgery patients: Implications of incidental findings

P. Njoku, I. Meka, N. Mbadiwe
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引用次数: 1

Abstract

Background: Dyslipidemia is an established risk factor for cardiovascular disease (CVD). Different schools of thought hold different opinions regarding the use of statins in the perioperative period for cardiac surgery patients. There seems not to be a consensus yet on when to commence statin therapy for cardiac surgery patients not yet on treatment for dyslipidemia, but the beneficial effects of dyslipidemia management are not in doubt. Objectives: The objective was to characterize the pattern of dyslipidemia and atherogenic indices present in cardiac surgery patients. Materials and Methods: The study was a retrospective record review of patients who presented for open heart surgery between 2013 and 2017. Results of pre-operative lipid profile of patients were extracted and analyzed using SPSS version 22. Atherogenic risk was determined using three different risk ratios: atherogenic plasma index and Castelli’s risk indices-I and II. Results: The study included a total of 51 adult patients with the age range 18–75 years and male: female ratio of 1:1.4. Dyslipidemia observed in participants was majorly in the form of low high-density lipoprotein 24 (49.0%) and elevated low-density lipoprotein 11 (22.5%). Using atherogenic plasma index, more than one-quarter of participants 15 (30.6%) were found to be in the high- and medium-risk groups. Conclusion: Incidental findings of dyslipidemia made in this group of patients have its associated health implications. Hence, it buttresses the importance of assessing for and adequate management of the medical condition, particularly in a group of patients already burdened with CVD.
心脏手术患者术前脂质谱:偶然发现的含义
背景:血脂异常是心血管疾病(CVD)的危险因素。对于他汀类药物在心脏手术患者围手术期的应用,不同的学派持有不同的观点。对于尚未接受血脂异常治疗的心脏手术患者,何时开始他汀类药物治疗似乎尚未达成共识,但血脂异常治疗的有益效果是毋庸置疑的。目的:目的是表征心脏手术患者血脂异常和动脉粥样硬化指数的模式。材料和方法:该研究是对2013年至2017年间接受心脏直视手术的患者的回顾性记录回顾。采用SPSS 22对患者术前血脂进行提取和分析。使用三种不同的风险比来确定动脉粥样硬化风险:动脉粥样硬化血浆指数和Castelli风险指数- i和II。结果:共纳入51例成年患者,年龄18 ~ 75岁,男女比例为1:1.4。在参与者中观察到的血脂异常主要表现为低高密度脂蛋白24(49.0%)和低密度脂蛋白11(22.5%)升高。使用致动脉粥样硬化血浆指数,发现超过四分之一(30.6%)的参与者处于高、中危组。结论:在这组患者中偶然发现的血脂异常具有相关的健康意义。因此,它支持了评估和适当管理医疗状况的重要性,特别是在一组已经患有心血管疾病的患者中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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