{"title":"Whoever goes slowly (after eating) goes far","authors":"F. Betti, Manuela Dadda, B. Ronchi, G. Traina","doi":"10.23750/abm.v93iS3.13071","DOIUrl":null,"url":null,"abstract":"Food-dependent exercise-induced anaphylaxis (FDEIA) is an uncommon IgE-mediated hypersensitivity disease with limited prevalence data. Recently, reported cases of FDEIA have been increasing both in adults and children. FDEIA pathogenetic mechanisms are not yet completely understood. Factors that add up their effects are food ingestion and physical effort and, in some cases, concomitant diseases, alcohol, drugs, emotional stress, menstruation, and particular weather conditions contribute to enhancing the reaction. Food-specific FDEIA (sFDEIA) implies the presence of an IgE-mediated sensitization to one or more foods, while in unspecific FDEIA (nsFDEIA), any food can induce anaphylaxis without sensitization. Among causative foods, the most dominant trigger of FDEIA is wheat, in particular the allergen ω-5 gliadin (Tri a 19). Other common foods are seafood, seeds, grains, nuts, vegetables and fruit, cow’s milk, meat, and eggs. We present three cases of sFDEIA in children with clinical features and laboratory findings; the first was induced by a culprit food less frequently involved in sFDEIA than the others (www.actabiomedica.it).","PeriodicalId":93849,"journal":{"name":"Acta bio-medica : Atenei Parmensis","volume":"39 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta bio-medica : Atenei Parmensis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23750/abm.v93iS3.13071","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Food-dependent exercise-induced anaphylaxis (FDEIA) is an uncommon IgE-mediated hypersensitivity disease with limited prevalence data. Recently, reported cases of FDEIA have been increasing both in adults and children. FDEIA pathogenetic mechanisms are not yet completely understood. Factors that add up their effects are food ingestion and physical effort and, in some cases, concomitant diseases, alcohol, drugs, emotional stress, menstruation, and particular weather conditions contribute to enhancing the reaction. Food-specific FDEIA (sFDEIA) implies the presence of an IgE-mediated sensitization to one or more foods, while in unspecific FDEIA (nsFDEIA), any food can induce anaphylaxis without sensitization. Among causative foods, the most dominant trigger of FDEIA is wheat, in particular the allergen ω-5 gliadin (Tri a 19). Other common foods are seafood, seeds, grains, nuts, vegetables and fruit, cow’s milk, meat, and eggs. We present three cases of sFDEIA in children with clinical features and laboratory findings; the first was induced by a culprit food less frequently involved in sFDEIA than the others (www.actabiomedica.it).
食物依赖性运动诱发过敏性反应(FDEIA)是一种罕见的ige介导的超敏性疾病,患病率数据有限。最近,报告的FDEIA病例在成人和儿童中都有所增加。FDEIA的发病机制尚不完全清楚。食物摄入和体力消耗,以及伴随的疾病、酒精、药物、情绪压力、月经和特殊的天气条件,这些因素加在一起会增强这种反应。食物特异性FDEIA (sFDEIA)意味着存在ige介导的对一种或多种食物的致敏,而在非特异性FDEIA (nsFDEIA)中,任何食物都可以诱导过敏反应而不致敏。在致病性食物中,FDEIA最主要的触发因素是小麦,特别是过敏原ω-5麦胶蛋白(Tri a 19)。其他常见的食物有海鲜、种子、谷物、坚果、蔬菜和水果、牛奶、肉和鸡蛋。我们报告三例儿童sFDEIA的临床特征和实验室结果;第一种是由一种罪魁祸首食物引起的,这种食物与sFDEIA的关系比其他食物要少(www.actabiomedica.it)。