Case Report of Successful IVF with Pregnancy of a 46 Year Old Lady after 12 Years Trials and 10 failed IVFs

Abstract

Background: In this study, we indicate the importance of a case, where specific diagnostic tests such as NK level, NK endometrial cells, NK activity, embryotoxicity (ETA), and PLA (platelet leukocyte aggregates) were used for investigating infertile women with many failed IVFs. Case presentation: We describe a very important case of unexplained infertility, where a 46 year old lady managed finally to get pregnant after 12 years of consecutive trials and 10 failed IVFs. Our center tested her for all 3 NK markers, ETA, and Vitamin D3, TSH, and PLA, which are essential for positive pregnancy. The lady was treated with intravenous solution of intralipid after the high NK result. She was administered with two dosages and then performed embryo transfer where after 10 days she received the positive pregnancy test result. Conclusion: The high evaluation of immune status based on the specific tests of NK panel (all 3 markers), ETA, and PLA can save time and money for couples that have attempted several embryo transfers in IVF centers with unsuccessful pregnancies. Also, the targeted individualized treatment of the couple can significantly increase the chances for successful pregnancy.