Macular Hole Following Retained Subfoveal PFCL

Navneet S. Mehrotra, G. Mohan, M. Nagpal, S. Talati, Ak Sharma
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Abstract

Introduction: Perfluorocarbon liquids (PFCLs) were first developed in 1970s as possible substitutes to erythrocytes because of their capacity to dissolve relatively large amounts of oxygen. Based on their properties, PFCL are widely used in complex retinal detachments, but they can cause complications in cases of subretinal retention. Migration of peripherally located subretinal PFCL towards the fovea is well established, but spontaneous resolution of sub-foveal PFCL without surgical evacuation or displacement has rarely been described. Case report: We report a case of a 48 year old male on whom a vitrectomy was performed for a retinal detachment with scleral tear following trauma. PFCL was used for ten days as a temporary intraocular tamponade for retinal flattening. A second vitrectomy was done to replace the PFCL with silicone oil, following which retained sub-foveal PFCL was noted. Result: Fourteen months later, a macular hole developed and PFCL disappeared. Slight superior displacement of the macular area was observed due to contraction of fibrous proliferation superiorly. There was no decrease in visual acuity. Patient was advised to undergo silicon oil removal. CONCLUSION: In the future, improved understanding of the mechanisms of spontaneous resolution may enable the development of non-surgical methods to displace sub-foveal PFCL.
黄斑裂孔后保留中央凹下PFCL
简介:全氟化碳液体(PFCLs)最早是在20世纪70年代开发的,作为红细胞的可能替代品,因为它们具有溶解相对大量氧气的能力。基于其特性,PFCL被广泛应用于复杂的视网膜脱离,但在视网膜下保留的情况下会引起并发症。周围定位的视网膜下PFCL向中央凹的迁移是很好的,但没有手术清除或移位的中央凹下PFCL自发解决很少被描述。病例报告:我们报告一个48岁的男性的情况下,玻璃体切除术进行视网膜脱离巩膜撕裂创伤后。PFCL作为暂时性眼内填塞使视网膜变平,使用10天。第二次玻璃体切除术用硅油代替PFCL,随后注意到保留了中央凹下PFCL。结果:14个月后出现黄斑孔,PFCL消失。由于纤维增生的收缩,可见黄斑区域有轻微的上移位。视力没有下降。建议患者进行硅油去除术。结论:在未来,对自发消退机制的进一步了解可能会促进非手术方法的发展,以取代中央凹下PFCL。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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