{"title":"001 UVA‐1 for the treatment of chronic hand dermatitis","authors":"B. Bergamo, C. Elmets","doi":"10.1034/J.1600-0781.2002.180208_1.X","DOIUrl":null,"url":null,"abstract":"UVA-1 has distinct immunological effects which has allowed it to be useful for a number of cutaneous diseases that have been relatively resistant to other treatment modalities. These include urticaria pigmentosa, morphea/scleroderma and T-cell mediated diseases such as atopic dermatitis and cutaneous T-cell lymphoma. Since chronic hand dermatitis is also mediated by T-cells, we hypothesized that UVA- 1 would be an effective treatment for that disease as well. Five subjects with recalcitrant hand dermatitis caused by dyshidrosis and/or chronic irritancy were treated with a medium dose regimen of UVA- 1. This consisted of 15 treatments of 60 J/cm2 UVA 1 over 3 weeks. Subjects received a total of 900 J/cm2. A clinical scoring parameter, Dyshidrotic Area and Seventy Index Score (DASI), was administered to subjects prior to and following the UVA- 1 treatment course. Clinical photographs were also taken. All subjects showed improvement in hand dermatitis as demonstrated by clinical photographs and the DASI score (13 ± 5.35 before treatment; 6.3 ± 4.50 after treatment). UVA- 1 is an effective and rapid acting treatment for chronic hand dermatitis.","PeriodicalId":20104,"journal":{"name":"Photodermatology, Photoimmunology and Photomedicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2002-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodermatology, Photoimmunology and Photomedicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1034/J.1600-0781.2002.180208_1.X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
UVA-1 has distinct immunological effects which has allowed it to be useful for a number of cutaneous diseases that have been relatively resistant to other treatment modalities. These include urticaria pigmentosa, morphea/scleroderma and T-cell mediated diseases such as atopic dermatitis and cutaneous T-cell lymphoma. Since chronic hand dermatitis is also mediated by T-cells, we hypothesized that UVA- 1 would be an effective treatment for that disease as well. Five subjects with recalcitrant hand dermatitis caused by dyshidrosis and/or chronic irritancy were treated with a medium dose regimen of UVA- 1. This consisted of 15 treatments of 60 J/cm2 UVA 1 over 3 weeks. Subjects received a total of 900 J/cm2. A clinical scoring parameter, Dyshidrotic Area and Seventy Index Score (DASI), was administered to subjects prior to and following the UVA- 1 treatment course. Clinical photographs were also taken. All subjects showed improvement in hand dermatitis as demonstrated by clinical photographs and the DASI score (13 ± 5.35 before treatment; 6.3 ± 4.50 after treatment). UVA- 1 is an effective and rapid acting treatment for chronic hand dermatitis.