Hormonal contraception and cervical cancer: does the correlation exist?

Abstract

The article presents a systematic analysis of scientifi c publications concerning the eff ect of combined hormonal contraceptives on the risk of the development of cervical cancer. The following databases were used for literary search: PubMed, Cochrane, Google Scholar, elibrary.ru. Key words and their combinations were: “cervical cancer”, “cervical intraepithelial neoplasia”, “human papillomavirus”, “contraception”, “combined oral contraceptives”, “hormonal contraceptives”. 147 scientifi c publications have been analyzed, and 10 of them have been selected with the use of I/E criteria. Based on the analyzed literature, a conclusion was made. Long-term use of combined oral contraceptives against the background of persistence of the human papillomavirus increases the risk of developing cervical cancer.