Pituitary involvement in a case of granulomatosis with polyangiitis: case report and literature review

Abstract

Granulomatosis with polyangiitis ) GPA, also known as Wegener’s ( is an anti-neutrophil cytoplasmic antibody-associated multisystem disease characterized by necrotizing small vessel vasculitis which mainly affects the upper and lower respiratory tracts as well as the kidneys. Involvement of the central nervous system is uncommon in GPA and might be difficult to treat. Pituitary involvement is a rare presentation in GPA. Presented herein is the case of a 28-year-old woman with GPA involving the pituitary gland and other systemic manifestations of the disease.