Screening of Antibacterial and Antioxidant Activity from the Soft Corals Sinularia sp. and Sarcophyton sp. Origin Palu Bay, Central Sulawesi, Indonesia

Q3 Environmental Science
W. A. Tanod, D. Dewanto, S. Ndobe, P. H. Riyadi, M. Putra
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引用次数: 8

Abstract

This study aimed to evaluate the potential antibacterial and antioxidant activities of Sinulariasp. and Sarcophyton sp. from the Palu Bay, Central Sulawesi, Indonesia. Soft corals were identified as Sinulariasp. (SC1), Sinularia sp. (SC2), andSarcophytonsp. (SC3). Antibacterial activity was examined using agar diffusion well method. Antioxidant activity was measured by the DPPH radical scavenging method. The samples were macerated in MeOH: DCM. The crude extracts were partitioned with DCM, EtOAc, and BuOH. The crude extract of Sinulariasp. (SC2) showed a very strong antibacterial activity as it was able to inhibit the growth of Staphylococcus aureusand Escherichia coliup to 10 mg/mL. Sinularia sp. (SC1) crude extract showed strong activity againstS. aureus, whereas it showed moderate against E. coli.Sarcophyton sp. (SC3) crude extract showed moderate activity against S. aureus, whereas it showed weak against E. coli. The partition fractions of the three soft coral extracts had the potential to be a potent antioxidant agent.
产自印度尼西亚苏拉威西岛中部帕卢湾的Sinularia sp.和Sarcophyton sp.软珊瑚抗菌和抗氧化活性的筛选
本研究旨在评价紫苏蒿潜在的抗菌和抗氧化活性。和来自印度尼西亚苏拉威西岛中部帕卢湾的石藻。软珊瑚鉴定为Sinulariasp。(SC1)、Sinularia sp. (SC2)和sarcophytonsp .。(SC3)。用琼脂扩散孔法测定其抑菌活性。采用DPPH自由基清除法测定其抗氧化活性。样品在MeOH: DCM中浸泡。粗提物分别用DCM、EtOAc和BuOH进行分割。菝葜粗提物。(SC2)对金黄色葡萄球菌和大肠杆菌的抑菌活性高达10 mg/mL,具有很强的抑菌活性。Sinularia sp. (SC1)粗提物具有较强的抗虫活性。而对大肠杆菌表现温和。Sarcophyton sp. (SC3)粗提物对金黄色葡萄球菌的活性中等,对大肠杆菌的活性较弱。这三种软珊瑚提取物的分割部分有可能成为一种有效的抗氧化剂。
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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
10
审稿时长
16 weeks
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