Assessment of Serum Level of Highly Sensitive C-reactive Protein (Hs-Crp) and Uric Acid among Adult Athletes in Aba Metropolis

V. O. Ikpeazu, J. Chikezie, L. Chigbu, S. Offiah, S. Umeh, N. Igboh
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Abstract

Purpose: The long-term positive effect of physical activity on the incidence of coronary artery disease, hypertension, dyslipidemia, obesity, and life expectancy are well known. This has led to many stressing the importance of exercising to promote optimal health. This study is therefore aimed at evaluating the effect of physical exercise on serum level of highly sensitive C-reactive protein (Hs-CRP) and Uric acid among adult athletes in Aba Metropolis of Abia State. Methodology: Hundred adults were used for the study. Fifty subjects served as control and were randomly selected. The remaining fifty, twenty-five were males and twenty-five were females. Thirteen out of the twenty-five males and females exercise regularly while twelve exercises seldom. However for inclusion criteria the person had to be an athlete and for exclusion criteria, persons with cardiovascular diseases, diabetes mellitus, stroke rheumatoid arthritis and those with chronic obstructive pulmonary diseases were excluded.  Blood sample was collected by venipuncture and was used to determine Highly Sensitive C-Reactive protein (Hs-CRP) and Uric Acid using Enzyme Linked Immunoassay machine and Semi automated Analyzer respectively. Data generated were analyzed using Statistical Package for Social Sciences (SPSS Version 25), One-way Analysis of Variance (ANOVA) and student t- test. Significance level for analysis was set at P-value 0.05 (P=<0.05). Findings: The result from the study revealed that regularly exercising athletes had significantly lower Hs-CRP values than the control group. Observed as well was that regularly exercising athletes had lower HsCRP values than seldom-exercising athletes. Conversely, the uric acid level of those that exercise regularly increased compared to those seldomly exercise. This study has yet added to the need and importance of exercise in order to stay in optimal health. Recommendation: People without health issue should be encouraged to exercise regularly but this should not be outside consulting their health care giver.                  
阿坝市区成年运动员血清高敏感c反应蛋白(Hs-Crp)和尿酸水平的评估
目的:体育锻炼对冠状动脉疾病、高血压、血脂异常、肥胖和预期寿命的长期积极影响是众所周知的。这导致许多人强调锻炼对促进最佳健康的重要性。因此,本研究旨在评估体育锻炼对阿比亚州阿坝市成年运动员血清高敏感c反应蛋白(Hs-CRP)和尿酸水平的影响。研究方法:研究对象为100名成年人。随机选取50名受试者作为对照。剩下的50只,25只雄性,25只雌性。25名男女中有13人经常锻炼,12人很少锻炼。然而,按照纳入标准,此人必须是运动员,而按照排除标准,患有心血管疾病、糖尿病、中风、风湿性关节炎和慢性阻塞性肺病的人被排除在外。静脉穿刺采血,分别用酶联免疫仪和半自动分析仪检测高敏感c反应蛋白(Hs-CRP)和尿酸。产生的数据分析使用社会科学统计软件包(SPSS Version 25),单因素方差分析(ANOVA)和学生t检验。P= 0.05为分析的显著性水平(P=<0.05)。研究结果:研究结果显示,经常锻炼的运动员的Hs-CRP值明显低于对照组。同样观察到的是,经常运动的运动员的HsCRP值低于很少运动的运动员。相反,经常运动的人的尿酸水平比很少运动的人高。这项研究进一步强调了锻炼的必要性和重要性,以保持最佳健康状态。建议:应该鼓励没有健康问题的人定期锻炼,但这应该咨询他们的医疗保健提供者。
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