Gerd-Q Score As Outcome Parameter Of Anterior vs. Posterior Peroral Endoscopical Myotomy in Acalasia Patient

Athala Rania Insyira, I. G. B. S. Mahendra, Ni Komang Ayu Trisnayanti Yasa, Nimas Resti, Nofiana Ayu Risqiana Sari, Catarina Budyono
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Abstract

Achalasia is an esophageal motility disorder which is characterized by relaxation failure of the lower esophageal sphincter and absence of distal esophageal peristalsis. The prevalence rate of achalasia is 10 cases per 100,000 population with dysphagia, regurgitation, chest pain, and weight loss as the main clinical manifestations. Target of treatment for achalasia is a decreased resting pressure in the lower esophageal sphincter and this can be achieved using peroral endoscopic myotomy (POEM). POEM can be performed using two therapeutic approaches: anterior and posterior. Complication that often occurs after POEM is Gastroesophageal Reflux Disease (GERD). GERD leads to symptoms and/or structural damage that affects the patient’s quality of life. The GERD questionnaire (GERD-Q) is a sensitive and non-invasive screening tool for diagnosing GERD. Based on the result analysis of this research that was conducted to assess the outcome of anterior and posterior POEM with the GERD-Q score parameter, there was no significant difference in scores between the anterior and posterior approaches.
Gerd-Q评分作为失弛缓症患者前后经口内窥镜肌切开术的预后参数
贲门失弛缓症是一种食管运动障碍,其特征是食管下括约肌松弛失败和食管远端蠕动缺失。失弛缓症的患病率为10例/ 10万人,主要临床表现为吞咽困难、反流、胸痛、体重减轻。贲门失弛缓症的治疗目标是降低食管下括约肌静息压,这可以通过经口内窥镜肌切开术(POEM)来实现。POEM可以采用两种治疗方法:前路和后路。POEM术后常见的并发症是胃食管反流病(GERD)。反流胃食管反流导致影响患者生活质量的症状和/或结构损伤。GERD问卷(GERD- q)是诊断GERD的一种灵敏、无创的筛查工具。本研究以GERD-Q评分参数评价前后路POEM的预后,结果分析显示前后路评分无显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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