Frequency of QT Interval Prolongation in Chronic Liver Disease Patients

W. Khan, Tahir Ullah Khan
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Abstract

Introduction: The frequency of QT interval prolongation as published in the international and local literature has been variable. Aims & Objectives: To determine the frequency of QT interval prolongation in patients with chronic liver disease and resolve the variability in the literature. Place and duration of study: The present study was conducted in Gastroenterology and Hepatology Unit Shaikh Zayed Hospital Lahore from 1st March 2017 to 31st August 2017. Material & Methods: About 240 patients with diagnosed chronic liver disease were selected. Electrocardiography (12 lead) was performed in all patients to look for QT interval prolongation and their mean was calculated for purpose of analysis. Results: Mean age of our patients was 53.7±11.9 and male gender was dominant (55.8%). It was noted that QT interval was prolonged in 62 patients (25.8%) while rest of the 178 patients had normal QT interval. Conclusion: QT interval prolongation is frequently observed (25.8%) in chronic liver disease patients. Therefore, every patient with chronic liver disease should be investigated for QT interval prolongation.
慢性肝病患者QT间期延长的频率
在国际和国内文献中发表的QT间期延长的频率是可变的。目的:确定慢性肝病患者QT间期延长的频率,并解决文献中的变异性。研究地点和时间:本研究于2017年3月1日至2017年8月31日在拉合尔谢赫扎耶德医院胃肠病学和肝病科进行。材料与方法:选取240例确诊为慢性肝病的患者。所有患者均行心电图(12导联)检查QT间期延长,并计算其平均值进行分析。结果:患者平均年龄53.7±11.9岁,男性居多(55.8%)。注意到QT间期延长62例(25.8%),其余178例QT间期正常。结论:慢性肝病患者QT间期延长较为常见(25.8%)。因此,每一位慢性肝病患者都应检查QT间期是否延长。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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