Clinical Significance of Laboratory Investigations for Immune Complexes

Abstract

CIC occur in numerous disorders. A review is given of the currently most widely used and best standardized immune complex assays and their clinical applications. Special emphasis is given to these disorders in which the results of IC assays have been shown to be of clinical importance to establish a diagnosis or prognosis or to monitor disease activity and treatment efficacy. The use of IC assays for this purpose is justified in only a relatively small number of disorders.