Trends and Applications of Molecular Distillation in Pharmaceutical and Food Industries

Separation & Purification Reviews Pub Date : 2021-06-13 DOI:10.1080/15422119.2021.1924205

Engy A. Mahrous, M. Farag

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引用次数: 7

Abstract

ABSTRACT Introduction Molecular distillation (MD) is a physical separation method that was developed for several applications in petrochemical, food, cosmetics and pharmaceutical industries. Early industrial applications were most prominent in the petrochemical industry and in the food industry for vegetable oil refinement. During the past two decades, MD has gained a renewed attention and its applications have expanded to include purification and enrichment of bioactive compounds from natural product extracts and in nutraceuticals production. Objectives This review highlights, from a chemical perispective, applications and potential future MD development in the fields of pharmaceutics and natural product chemistry. Literature review A brief summary to outline the MD concept and the factors to be considered in designing efficient MD experiments is provided. Recent MD applications in the production and refinement of raw materials to be used in the pharmaceutical, cosmetics and nutraceutical industries are analyzed. This review further discusses future development in MD to expand its appliaction for refinement and purification of fixed oils, essential oils and plant extracts.

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分子蒸馏在制药和食品工业中的发展趋势和应用

分子蒸馏(MD)是一种用于石油化工、食品、化妆品和制药等行业的物理分离方法。早期的工业应用在石油化工工业和食品工业中对植物油的精炼最为突出。在过去的二十年中，MD获得了新的关注，其应用范围已经扩大到包括从天然产品提取物和营养保健品生产中纯化和富集生物活性化合物。本文从化学的角度综述了MD在制药和天然产物化学领域的应用和潜在的发展前景。简要概述了MD的概念和设计有效MD实验时应考虑的因素。分析了最近MD在制药、化妆品和营养保健行业原料生产和精制中的应用。本文对其在固定油、精油和植物提取物的精制纯化方面的应用前景进行了展望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Separation & Purification Reviews

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