Report of the Association Between Multisystem Inflammatory Syndrome and Severe Myocarditis

IF 0.4 4区医学 Q4 PEDIATRICS

Iranian Journal of Pediatrics Pub Date : 2023-04-09 DOI:10.5812/ijp-122272

Elmira Hajiesmaeil Memar, A. Zeinaloo, M. Mirzaaghayan, Mojtaba Gorji, A. Ghamari, Mahya Ghahremanloo, Ehsan Aghaei-Moghadam

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引用次数: 0

Abstract

Introduction: The people worldwide have been affected by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection since its appearance in December, 2019. Kawasaki disease-like hyperinflammatory shock associated with SARS-CoV-2 infection in previously healthy children has been reported in the literature, which is now referred to as a multisystem inflammatory syndrome in children (MIS-C). Some aspects of MIS-C are similar to those of Kawasaki disease, toxic shock syndrome, secondary hemophagocytic syndrome, and macrophage activation syndrome. Case Presentation: This study reported an 11-year-old boy with MIS-C presented with periorbital and peripheral edema, abdominal pain, elevated liver enzymes, severe right pleural effusion, moderate ascites, and severe failure of right and left ventricles. Conclusions: Due to the increasing number of reported cases of critically ill patients afflicted with MIS-C and its life-threatening complications, it was recommended that further studies should be carried out in order to provide screening tests for myocardial dysfunction. Adopting a multidisciplinary approach was found inevitable.

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多系统炎症综合征与严重心肌炎的相关性报道

自2019年12月出现严重急性呼吸综合征-冠状病毒2 (SARS-CoV-2)感染以来，全世界的人都受到了影响。文献中已经报道了先前健康儿童中与SARS-CoV-2感染相关的川崎病样高炎症性休克，现在称为儿童多系统炎症综合征(MIS-C)。misc在某些方面与川崎病、中毒性休克综合征、继发性噬血细胞综合征和巨噬细胞激活综合征相似。病例介绍:本研究报告了一名11岁的misc男孩，表现为眼眶周围和周围水肿、腹痛、肝酶升高、严重的右侧胸腔积液、中度腹水和严重的左右心室衰竭。结论:由于报道的危重患者misc及其危及生命的并发症的病例越来越多，建议开展进一步的研究，以提供心肌功能障碍的筛查试验。采取多学科方法是不可避免的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Iranian Journal of Pediatrics 医学-小儿科

CiteScore

0.90

自引率

20.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Iranian Journal of Pediatrics (Iran J Pediatr) is a peer-reviewed medical publication. The purpose of Iran J Pediatr is to increase knowledge, stimulate research in all fields of Pediatrics, and promote better management of pediatric patients. To achieve the goals, the journal publishes basic, biomedical, and clinical investigations on prevalent diseases relevant to pediatrics. The acceptance criteria for all papers are the quality and originality of the research and their significance to our readership. Except where otherwise stated, manuscripts are peer-reviewed by minimum three anonymous reviewers. The Editorial Board reserves the right to refuse any material for publication and advises that authors should retain copies of submitted manuscripts and correspondence as the material cannot be returned. Final acceptance or rejection rests with the Editors.