EPISODES OF HEARTBURN AND BLOATING IN MEDICAL PRACTICE

Vazha Gvantseladze, Nana Gnantseladze
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Abstract

The aim of the study was to study the frequency and nature of episodes of heartburn and bloating in patients with duodenal and gastric ulcers in the Georgian population, considering the histomorphological and morphometric changes of the gastric mucosa and the parameters of gastric secretion. At the same time, we were interested in analyzing patients' anamnesis before being hospitalized for the last 2 months. The analysis of the material showed that incidence of heartburn episodes in the Georgian population is clearly higher in patients with peptic ulcer disease 12 - (79.9%) than in patients with gastric ulcer (9 - 31.9%). Episodes of heartburn in these patients are characterized not only by increasing of rate (more than 50 episodes), both day and night, but the intensity and duration (which is due to abnormal gastroesophageal reflux). This is a high risk for the occurrence of heartburn episodes. As for bloating, it was detected in patients with duodenal ulcer (11–26.2%), in gastric ulcer 11– (32.9%). The main pathogenetic aspects of heartburn episodes were found to be diffuse fundal glands hyperplasia and high acidity (duodenal ulcer and pyloric anterior ulcer). It was also found that a large percentage of patients were not treated properly, leading to impaired ability to work and changes in quality of life and disease progression.
医疗实践中胃灼热和腹胀的发作
该研究的目的是研究格鲁吉亚人群中十二指肠溃疡和胃溃疡患者胃灼热和腹胀发作的频率和性质,考虑胃粘膜的组织形态学和形态计量学变化以及胃分泌参数。同时,我们有兴趣分析最近2个月患者住院前的记忆情况。资料分析显示,格鲁吉亚人群中消化性溃疡患者的胃灼热发生率(79.9%)明显高于胃溃疡患者(9.31.9%)。这些患者的胃灼热发作不仅表现为白天和夜间发生率增加(超过50次),而且表现为强度和持续时间增加(这是由于胃食管反流异常)。这是发生胃灼热发作的高风险。胃胀以十二指肠溃疡患者(11 - 26.2%)、胃溃疡患者(11 - 32.9%)为主。胃灼热发作的主要病因是弥漫性基底腺增生和高酸性(十二指肠溃疡和幽门前溃疡)。研究还发现,很大比例的患者没有得到适当的治疗,导致工作能力受损、生活质量改变和疾病进展。
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