A social and Biological Approach for Postpartum Depression in Egypt

Hagar A. Mohamed , Sandra L. Spencer , Abdo H. Al Swasy , Sahar E. Swidan , Mohamed S. Abouelenien
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引用次数: 2

Abstract

Postpartum depression (PPD) is a major health problem that affects many women worldwide. In Egypt, PPD is neglected despite the expected high prevalence rate among women during the transition period after the Egyptian revolution. This research investigated the prevalence, risk factors, and interventions of postpartum depression in southern rural Egypt. Interviews were conducted with 57 participants recruited from public and private hospitals. Questionnaires and the Arabic version of the Edinburgh Postnatal Depression Scale were administered. The prevalence of PPD was found to be 73.7% and is associated with low income and age at childbirth. Most participants regarded screening mothers after childbirth for PPD as an effective way to detect and intervene in PPD; in comparison to, antidepressants that were regarded by most participants as ineffective. Furthermore, in an effort to assess the cultural-suitability of prescribing antidepressants for PPD in such communities, where high pregnancy rate is favored, we examined the biological influence of Sertraline, a widely prescribed antidepressant medication, on the FSH and LH gene expression and discussed its possible effects on fertility based on our results.

埃及产后抑郁症的社会和生物学研究
产后抑郁症(PPD)是影响全世界许多妇女的主要健康问题。在埃及,尽管预期妇女在埃及革命后的过渡时期发病率很高,但产后肺病却被忽视。本研究调查了埃及南部农村地区产后抑郁症的患病率、危险因素和干预措施。采访了从公立和私立医院招募的57名参与者。问卷调查和阿拉伯语版的爱丁堡产后抑郁量表被执行。PPD患病率为73.7%,与低收入和分娩年龄有关。大多数参与者认为产后母亲PPD筛查是发现和干预PPD的有效方法;相比之下,大多数参与者认为抗抑郁药无效。此外,为了评估在这些高妊娠率的社区开具抗抑郁药物治疗产后抑郁症的文化适应性,我们检查了舍曲林(一种广泛使用的抗抑郁药物)对FSH和LH基因表达的生物学影响,并根据我们的结果讨论了其对生育能力的可能影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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