Evaluating advanced glycation end products by the clinical effects of Astragali Radix using skin autofluorescence

Shunsuke Watanabe, Shigeo Aoyama
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Abstract

Advanced glycation end products (AGEs) associated with diabetes, renal failure, and non‐alcoholic fatty liver disease have recently been receiving attention. The present study aimed to investigate therapeutic effects of Astragali Radix (AR) using skin autofluorescence (SAF) to evaluate AGEs. Treatment group (May 2019 to May 2020) was 18 patients. AR administration period was six months. SAF, body mass index, mean blood pressure, hemoglobin A1c, serum creatinine, estimated glomerular filtration rate (eGFR), aspartate transaminase, and alanine transaminase (ALT) were used.
皮肤自体荧光法评价黄芪晚期糖基化终产物的临床效果
晚期糖基化终产物(AGEs)与糖尿病、肾功能衰竭和非酒精性脂肪肝疾病相关,最近受到了人们的关注。本研究旨在利用皮肤自体荧光(SAF)评价黄芪(Astragali Radix, AR)对AGEs的治疗作用。治疗组(2019年5月~ 2020年5月)18例。AR给药期为6个月。SAF、体重指数、平均血压、血红蛋白A1c、血清肌酐、估计肾小球滤过率(eGFR)、天冬氨酸转氨酶和丙氨酸转氨酶(ALT)。
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