The Association of Serum 25-Hydroxyvitamin D Status in Patients with Osteoarthritis in the Primary Care Office

C. Ward, K. Contino, Akshar H. Patel, Eben Eno Mbei, Satyajeet Roy, K. Hunter, S. Gandhi
{"title":"The Association of Serum 25-Hydroxyvitamin D Status in Patients with Osteoarthritis in the Primary Care Office","authors":"C. Ward, K. Contino, Akshar H. Patel, Eben Eno Mbei, Satyajeet Roy, K. Hunter, S. Gandhi","doi":"10.4103/1947-2714.175216","DOIUrl":null,"url":null,"abstract":"Background: Low serum 25-hydroxyvitamin D [25(OH)D] and osteoarthritis (OA) are commonly found in patients followed up in a primary care office. Clear evidence to support the link between 25-hydroxyvitamin D levels and OA is lacking. Aim: To describe the association of serum 25-hydroxyvitamin D status in patients with OA in the primary care office. Materials and Methods: We reviewed the records of 1,455 patients seen in our primary care office between November 2013 and October 2014. All patients were older than 18 years and had a diagnosis of OA. Demographic characteristics as well as 25(OH)D levels and comorbidities were analyzed. Results: Levels of 25(OH)D were available in 1,222 patients with OA. Fifty-one percent of the patients had a low 25(OH)D level. Patients with OA and low 25(OH)D were on an average 5 years younger than patients with OA and normal 25(OH)D (P < 0.001). African Americans (71.7%) and Hispanics (63.1%) had a higher prevalence of low 25(OH)D compared to Whites (42.9%) and other races (49.1%) (P < 0.001). There were significantly more smokers (15.4%) and patients with type 2 diabetes (27.6%) in the group of patients with osteoarthritis and low 25(OH)D (P < 0.001). A lower prevalence of hypothyroidism (18.5% versus 27.4%) and higher body mass index (BMI) were also noted in the group of interest. Conclusion: Patients with low levels of 25(OH)D and OA are younger than their counterparts with low 25(OH)D level. Future studies are needed to clarify the relationship between 25(OH)D level and OA.","PeriodicalId":19703,"journal":{"name":"North American Journal of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"North American Journal of Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/1947-2714.175216","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

Abstract

Background: Low serum 25-hydroxyvitamin D [25(OH)D] and osteoarthritis (OA) are commonly found in patients followed up in a primary care office. Clear evidence to support the link between 25-hydroxyvitamin D levels and OA is lacking. Aim: To describe the association of serum 25-hydroxyvitamin D status in patients with OA in the primary care office. Materials and Methods: We reviewed the records of 1,455 patients seen in our primary care office between November 2013 and October 2014. All patients were older than 18 years and had a diagnosis of OA. Demographic characteristics as well as 25(OH)D levels and comorbidities were analyzed. Results: Levels of 25(OH)D were available in 1,222 patients with OA. Fifty-one percent of the patients had a low 25(OH)D level. Patients with OA and low 25(OH)D were on an average 5 years younger than patients with OA and normal 25(OH)D (P < 0.001). African Americans (71.7%) and Hispanics (63.1%) had a higher prevalence of low 25(OH)D compared to Whites (42.9%) and other races (49.1%) (P < 0.001). There were significantly more smokers (15.4%) and patients with type 2 diabetes (27.6%) in the group of patients with osteoarthritis and low 25(OH)D (P < 0.001). A lower prevalence of hypothyroidism (18.5% versus 27.4%) and higher body mass index (BMI) were also noted in the group of interest. Conclusion: Patients with low levels of 25(OH)D and OA are younger than their counterparts with low 25(OH)D level. Future studies are needed to clarify the relationship between 25(OH)D level and OA.
初级保健办公室骨关节炎患者血清25-羟基维生素D水平的相关性
背景:低血清25-羟基维生素D [25(OH)D]和骨关节炎(OA)常见于在初级保健办公室随访的患者。缺乏明确的证据支持25-羟基维生素D水平与OA之间的联系。目的:描述初级保健办公室OA患者血清25-羟基维生素D水平的相关性。材料与方法:我们回顾了2013年11月至2014年10月在我们初级保健办公室就诊的1455例患者的记录。所有患者年龄均大于18岁,均诊断为OA。分析人口统计学特征、25(OH)D水平及合并症。结果:1222例OA患者检测到25(OH)D水平。51%的患者有较低的25(OH)D水平。OA和低25(OH)D患者比OA和正常25(OH)D患者平均年轻5岁(P < 0.001)。非裔美国人(71.7%)和西班牙裔美国人(63.1%)的低25(OH)D患病率高于白人(42.9%)和其他种族(49.1%)(P < 0.001)。低25(OH)D骨性关节炎组吸烟者(15.4%)和2型糖尿病患者(27.6%)明显多于25(OH)D骨性关节炎组(P < 0.001)。甲状腺功能减退的患病率较低(18.5%对27.4%),体重指数(BMI)较高。结论:25(OH)D和OA水平低的患者比25(OH)D水平低的患者更年轻。25(OH)D水平与OA之间的关系有待进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信