The high lymphadenopathy and subcutaneous edema are associated with development of foot ulcer in type 2 diabetes: A collagen implanted antibiotic therapy
Karthikeyan Elumalai , Chittiboyena Sai Chaithanya Yadhav , Shaik Sana Nishad , Sivaneswari Srinivasan , Kamani Mounika , Srinivasan Sivannan , Kota Supriya , Anil Kumar
{"title":"The high lymphadenopathy and subcutaneous edema are associated with development of foot ulcer in type 2 diabetes: A collagen implanted antibiotic therapy","authors":"Karthikeyan Elumalai , Chittiboyena Sai Chaithanya Yadhav , Shaik Sana Nishad , Sivaneswari Srinivasan , Kamani Mounika , Srinivasan Sivannan , Kota Supriya , Anil Kumar","doi":"10.1016/j.bfopcu.2018.03.002","DOIUrl":null,"url":null,"abstract":"<div><p>The infective diabetic foot ulcer was caused by the high microbial infection affecting the surrounding tissue of the foot. The distal region of a foot was affected by the microbial infection in an uncontrolled situation. In this study, the possible efforts were made to prevent the diabetic foot ulcer of a patient. The diabetic foot ulcer, with tissue exposure and microbial infection on the surface of the foot, was treated with several antibiotics and dressings. The revascularization treatment procedure was started. The infection was reduced when compared with the beginning of this treatment. The collagen implant along with Gentamicin sulphate found that collagen was penetrated into the wound and helped the granulation of the tissue formation. The topical gentamicin reduced the bacterial contamination and cicatrization. The infective diabetic foot ulcer was treated by weekly dressings with collagen implant Gentamicin sulphate, Doxycycline, and Vancomycin therapy. It suggests that this combination will accelerate the healing of diabetic foot ulcer.</p></div>","PeriodicalId":9369,"journal":{"name":"Bulletin of Faculty of Pharmacy, Cairo University","volume":"56 1","pages":"Pages 101-103"},"PeriodicalIF":0.0000,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bfopcu.2018.03.002","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Faculty of Pharmacy, Cairo University","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1110093118300036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
The infective diabetic foot ulcer was caused by the high microbial infection affecting the surrounding tissue of the foot. The distal region of a foot was affected by the microbial infection in an uncontrolled situation. In this study, the possible efforts were made to prevent the diabetic foot ulcer of a patient. The diabetic foot ulcer, with tissue exposure and microbial infection on the surface of the foot, was treated with several antibiotics and dressings. The revascularization treatment procedure was started. The infection was reduced when compared with the beginning of this treatment. The collagen implant along with Gentamicin sulphate found that collagen was penetrated into the wound and helped the granulation of the tissue formation. The topical gentamicin reduced the bacterial contamination and cicatrization. The infective diabetic foot ulcer was treated by weekly dressings with collagen implant Gentamicin sulphate, Doxycycline, and Vancomycin therapy. It suggests that this combination will accelerate the healing of diabetic foot ulcer.