Fe3O4@SiO2@D-NHCS-Tr as Efficient and Reusable Catalyst for the Synthesis of indol-3-yl-4H-chromene via a Multi-Component Reaction Under Solvent-Free Conditions

Abstract

Fe 3 O 4 @SiO 2 @D-NHCS-Tr was used as an efficient catalyst in the three-component reaction between indole derivatives , salicylaldehyde and active methylene compounds under solvent-free conditions to the synthesis of indol-3-yl-4 H -chromene derivatives. The features of this method include the green conditions of the reaction, easy separation, eco-friendly and cost-effectiveness of the catalyst, and high yield in short reaction times