A HIGH PREOPERATIVE NEUTROPHIL-LYMPHOCYTE RATIO AS AN INDICATOR OF EARLY RESPONSE OF KIDNEY TRANSPLANT

Tanaya Ghinorawa, Gilang Samudera, Indrawarman Soeroharjo, A. Z. Hendri, Andy Zulfiqqar
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Abstract

Objective: This study aims to evaluate the association of the preoperative Neutrophil-lymphocyte ratio (NLR) and postoperative creatinine levels after kidney transplantation, which is a predictor factor for determining early postoperative transplantation complications. Material & Methods: We conducted a retrospective study of 33 patients enrolled in Sardjito General Hospital in Yogyakarta between 2017 and 2020. In this study, we observed the preoperative NLR and compared it with the postoperative creatinine level. The data were compared and analyzed. Results: This study showed that preoperative NLR in these 33 patients was 4.17 + 2.82. Postoperative creatinine levels were 2.38 + 1.75 mg/dL. Postoperative creatinine levels were higher in patients with low preoperative NLR (p=0.00). Besides, the correlation is weak and had a positive correlation direction (r=0.379). Conclusion: This study showed preoperative NLR and the postoperative serum creatinine level is correlated even weakly. NLR could be considered a predictor factor for determining postoperative transplantation complications, and even it still needs further research.
高术前中性粒细胞-淋巴细胞比率作为肾移植早期反应的指标
目的:本研究旨在评价肾移植术后术前中性粒细胞淋巴细胞比率(NLR)与术后肌酐水平的关系,这是确定肾移植术后早期并发症的一个预测因素。材料与方法:我们对2017年至2020年在日惹Sardjito总医院登记的33名患者进行了回顾性研究。在本研究中,我们观察术前NLR并与术后肌酐水平进行比较。对数据进行比较分析。结果:33例患者术前NLR为4.17 + 2.82。术后肌酐水平为2.38 + 1.75 mg/dL。术前NLR低的患者术后肌酐水平较高(p=0.00)。相关性较弱,呈正相关方向(r=0.379)。结论:术前NLR与术后血清肌酐水平相关性较弱。NLR可作为确定移植术后并发症的预测因素,但仍需进一步研究。
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