Acute Normovolemic hemodilution during CABG induces diastolic dysfunction: A perioperative transesophageal echocardiographic study

Abstract

Background and Goal of Study: A previous study has shown that Acute Normovolemic Hemodilution (ANH) during CABG improves diastolic function.1 It is however based on transmitral doppler indices that are preload dependent.2 Tissue doppler imaging (TDI) could overcome this problem. Materials and Methods: Af ter Ethical approvement and informed consent, 51 patients (subgroup of another study) with normal systolic function and hemoglobin values were prospectively randomized to ANH group or C (control) group. In ANH group, a precalculated amount of blood was withdrawn and replaced with colloids af ter the induction of anesthesia. Hemodynamic and echocardiographic parameters were recorded af ter anesthesia induction (T0), af ter ANH (T1) and 15 minutes post sternotomy (T2). Af ter the confirmation of normal distribution, student t-test was used. Results and Discussion: The demographic data of the patients are shown in table 1.