Susceptibility of Male who Have Sex with Male to High-Risk Type Human Papillomavirus (HPV) 16 and 18 with Condyloma Acuminata

P. Mawardi, Danu Yuliarto
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Abstract

Background: Condyloma acuminatum (CA) or genital warts are sexually transmitted infections caused by human papillomavirus (HPV). It is estimated that CA occurs in >80% of reproductive age in many countries, with the most common subtypes being 6 and 11. Purpose: The aim of the study to reveal the high risk (HR)-HPV in various condyloma acuminata in Dr. Moewardi Hospital. Methods: This study was a cross-sectional analytical observational study that assessed data collection concurrently over time. Specimens were patients diagnosed with condyloma acuminatum, biopsies were performed, and immunohistochemical staining was also performed. The sampling technique used sequential sampling, and the inclusion criteria included patients who came to our hospital for treatment. Results: The majority of the male sample was MSM. According to HIV status, 6 (30%) male patients were found to be positive. Immunohistochemistry showed that 15% of the samples were HR-HPV. Statistical test results for HR-HPV and low-risk (LR) HPV were significant, p-value = 0.038. Conclusion: Condyloma acuminatum is a sexually transmitted infection that usually occurs at the same time as HIV infection. In our study all patients with HR-HPV were MSM.
男性性行为者对高危型人乳头瘤病毒(HPV) 16和18伴尖锐湿疣的易感性
背景:尖锐湿疣(CA)或生殖器疣是由人乳头瘤病毒(HPV)引起的性传播感染。据估计,在许多国家,CA发生在80至80岁的育龄人口中,最常见的亚型是6和11。目的:本研究旨在揭示Moewardi医生医院各种尖锐湿疣的高危(HR)-HPV。方法:本研究是一项横断面分析性观察研究,评估随时间同时收集的数据。标本为诊断为尖锐湿疣的患者,进行了活检,并进行了免疫组织化学染色。抽样方法采用序贯抽样,纳入标准为来我院就诊的患者。结果:男性样本以男男性行为者居多。根据HIV感染情况,男性患者6例(30%)呈阳性。免疫组化显示15%的样本为HR-HPV。HR-HPV和低危(LR) HPV的统计学检验结果有显著性差异,p值= 0.038。结论:尖锐湿疣是一种性传播感染,通常与HIV感染同时发生。在我们的研究中,所有感染HR-HPV的患者都是男男性行为者。
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