EVALUATION OF EFFECTIVENESS OF COMPREHENSIVE TREATMENT OF DUODENAL ULCER IN CHILDREN

Abstract

In the structure of pathology of the digestive organs 1.7–16% constitute peptic ulcerdisease, which in 90% of cases is associated with H.pylori infection.The aim is to evaluate the effectiveness of comprehensive treatment of duodenal ulcer inchildren.Material and methods: The study included 60 children at the age of 10 -18 years withHelicobacter pylori-associated duodenal ulcer (DU), who were divided into three groupsof 20 people depending on the treatment regimen (protocol, including the donor of nitrogen monoxide and capillary stabilizing preparation).Results. Complex therapy of the disease in children provides faster positive dynamics ofclinical and endoscopic symptoms, increases the frequency of eradication of Helicobacterpylori, the relative risk of recurrence will decrease by 0.57 times when included in thetreatment regimen of nitrogen oxide donor and 0.66 times when used along with theprotocol scheme of the donor nitrogen oxide and capillarotropic drug.Conclusion. Comprehensive treatment of DU provides more stable results of treatmentand decreases the disease recurrences both in the early and late stages of observation.