Development of colloidal bio-nano drug for anticancer studies

R. Lavanya, S. A. John
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Abstract

The exploitation of bio (plant) materials for the biosynthesis of nanoparticles is considered a green technology as it does not involve any harmful chemicals. The present study reports the raw plant extraction and synthesis of gold (Au) nanoparticles from HAuCl4 using the powder of novel C. guianensis. The secondary metabolites were responsible for the reduction of gold metal to nano-sized Au nanoparticles. The 50% (IC50) value of cytotoxic activity was observed in 50 L concentration of sample and was enough to control the cancerous HeLa cells.
胶体生物纳米抗癌药物的研究进展
利用生物(植物)材料生物合成纳米粒子被认为是一种绿色技术,因为它不涉及任何有害化学物质。本研究报道了以新型桂树粉末为原料,从HAuCl4中提取并合成金(Au)纳米颗粒的方法。次级代谢物负责将金金属还原为纳米尺寸的金纳米颗粒。在50 L浓度下观察到50% (IC50)的细胞毒活性,足以控制癌变的HeLa细胞。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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