Muhammad Hassan, Fatima Mustafa, N. Khan, Taimoor Hassan, Mansoor Iqbal Chaudhry, M. Badshah
{"title":"SARS-CoV-2 infection with polymyositis- a case report","authors":"Muhammad Hassan, Fatima Mustafa, N. Khan, Taimoor Hassan, Mansoor Iqbal Chaudhry, M. Badshah","doi":"10.56310/pjns.v17i04.170","DOIUrl":null,"url":null,"abstract":"Among the most prevalent and least addressed symptoms of SARS-CoV-2 infection are myalgia, muscle weakness, and body aches. Only a few studies have reported polymyositis in patients with Covid-19 infection. At least one-third of patients with Covid-19 syndrome had elevated CPK levels. The cause of elevated CPK can be a cytokine storm or viral infection of the muscles. We present a case in which our patient developed features of myositis following the resolution of an acute viral prodrome caused by SARS-CoV-2. Our patient had both radiological and biopsy-proven neuromuscular manifestations of SARS-CoV-2 associated with polymyositis. Proximal muscle weakness began shortly after the resolution of the initial infection and progressed gradually over weeks or months, resulting in immobility. In the aftermath of investigations, the patient was diagnosed with polymyositis, appropriate treatment was started, and he showed signs of improvement.","PeriodicalId":19818,"journal":{"name":"Pakistan Journal of Neurological Sciences","volume":"18 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan Journal of Neurological Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.56310/pjns.v17i04.170","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Among the most prevalent and least addressed symptoms of SARS-CoV-2 infection are myalgia, muscle weakness, and body aches. Only a few studies have reported polymyositis in patients with Covid-19 infection. At least one-third of patients with Covid-19 syndrome had elevated CPK levels. The cause of elevated CPK can be a cytokine storm or viral infection of the muscles. We present a case in which our patient developed features of myositis following the resolution of an acute viral prodrome caused by SARS-CoV-2. Our patient had both radiological and biopsy-proven neuromuscular manifestations of SARS-CoV-2 associated with polymyositis. Proximal muscle weakness began shortly after the resolution of the initial infection and progressed gradually over weeks or months, resulting in immobility. In the aftermath of investigations, the patient was diagnosed with polymyositis, appropriate treatment was started, and he showed signs of improvement.