On the mechanism of titanocenedichloride-catalysed hydromagnesiation of alkynes with alkyl Grignard reagents

Abstract

The mechanism of titanocenedichloride-catalysed hydromagnesiation reaction of alkynes with an alkyl Grignard reagent is elucidated and it is revealed that the regiochemistry of the reaction controlled at the step of transmetallation from titanium to magnesium.