SPASMOLYTIC, ANTI-INFLAMMATORY, AND ANTIOXIDANT ACTIVITY OF SALVIA GESNERIFLORA LINDLEY

African Journal of Traditional, Complementary and Alternative Medicines Pub Date : 2018-10-16 DOI:10.21010/AJTCAM.V15I4.10

Abraham Gómez-Rivera, M. González-Cortázar, Ammy Joana Gallegos-García, Armando Escobar-Ramos, G. Flores‐Franco, C. E. Lobato-García

引用次数: 4

Abstract

Background: Salvia gesneriflora Lindley is employed in traditional Mexican medicine for the treatment of several diseases. Materials and Methods: The chromatographic profile of three extracts (SgH, SgD and SgM) of this plant allowed the identification of 11 components in SgH, the presence of rosmarinic (1), chlorogenic (2) and caffeic (3) acids and quercetin glucoside (4) in SgM and of ursolic acid (5) in SgD. The spasmolytic (electrically induced contractions of guinea-pig ileum), anti-inflammatory (edema in mouse ear) and antioxidant potential (DPPH, ABTS and FRAP assays) of the extracts were evaluated. Results: SgM showed the highest percentage of relaxation (80.67 ± 1.633%) with no significant difference (p

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鼠尾草的解痉、抗炎和抗氧化活性

背景:丹参在墨西哥传统医学中用于治疗多种疾病。材料与方法:对该植物的三种提取物(SgH、SgD和SgM)进行色谱分析，鉴定出SgH中的11种成分，SgM中存在迷迭香(1)、绿原(2)、咖啡酸(3)和槲皮素葡萄糖苷(4)，SgD中存在熊果酸(5)。评价各提取物的解痉(豚鼠回肠电致收缩)、抗炎(小鼠耳水肿)和抗氧化(DPPH、ABTS和FRAP测定)能力。结果:SgM松弛率最高(80.67±1.633%)，两组间差异无统计学意义(p < 0.05)

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来源期刊

African Journal of Traditional, Complementary and Alternative Medicines 医学-全科医学与补充医学

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The “African Journal of Traditional, Complementary and Alternative Medicines (AJTCAM)” is a peer-reviewed, multidisciplinary, international, scientific Open Access Journal that provides publication of articles on phytomedicines, ethnomedicines and veterinary ethnomedicines. The journal is published by a Non-Governmental Organization (NGO) known as “African Traditional Herbal Medicine Supporters Initiative (ATHMSI)”. The Journal welcomes submission of manuscripts that meet the general criteria of significance and scientific excellence. Papers will be published approximately two-to-three months after acceptance