TWO-PHOTON LUMINESCENCE AND SECOND HARMONIC GENERATION OF SINGLE LAYER MOLYBDENUM DISULPHIDE NANOPROBE FOR NONBLEACHING AND NONBLINKING OPTICAL BIOIMAGING

Abstract

Layered molybdenum disulphide (MoS2) can efficiently emit photoluminescence (PL) excited by visible light. However, one-photon PL of MoS2 for bioimaging purposes suffers from strong autofluorescence and ion-induced PL quenching. Herein, we report single layer chitosan decorated MoS2 nanosheets as nonbleaching and nonblinking optical nanoprobes under near infrared femtosecond laser excitation and their applications for two photon luminescence (TPL) and second harmonic generation (SHG) bioimaging. The TPL can resist the ion-induced quenching by the cellular membrane. The proposed TPL and SHG of single layer MoS2 show great potential for real-time, deep and multiphoton bioimaging.