Pharmacological Study and Phytochemical Study of Celastrus paniculatus Seed

Tejashri S. Shinde, Ravindra S. Jadhav, Dattaprasad N. Vikhe
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Abstract

The Celastrus paniculatus wild belongs to family Celastraceae. In Ayurveda is known as ‘Tree of life’ and ‘Elixir of life’. It is commonly known as Malkangani and Jyothishmati in Hindi and Sanskrit respectively. The plant contains bioactive compound such as Alkaloids, Tannins, Flavonoids, Saponins, Steroids, Terpenoids, Phlobatannins, Cardiac Glycosides and Phenolic Compound. seed oil are the most used parts of this deciduous plant and oral and intranasal routes are most preferred for delivering this drug in Ayurveda. Different studies have show that it has various pharmacological activities which involve neuroprotective activity, rejuvenative activity, cardiovascular activity, analgesic activity, anti-inflammatory activity, anti-infertility activity, antioxidant activity, free radical scavenging activity anti-arthritic activity etc. Mainly oil from seeds is used for stimulating intellect, sharpening memory and in the treatment of brain related disorder of all the age category. It also reported as a potential nervine tonic, rejuvenator and an anti-depressant. Celastrus paniculatus Willd is one of the medicinal plant having its importance in health care system as a indegenous medicinal plant also. The seed involve steroid alkaloids and bright natural coloring matter, celapanine, celapanigine, celapagine, celastrine, and paniculatine are the important alkaloids.
芹菜种子的药理研究和植物化学研究
野生大白菜属大白菜科。在阿育吠陀被称为“生命之树”和“生命的长生不老药”。它在印地语和梵语中分别被称为Malkangani和Jyothishmati。该植物含有生物碱、单宁、黄酮类、皂苷、类固醇、萜类、酞菁、心脏苷类和酚类化合物等生物活性化合物。种子油是这种落叶植物中最常用的部分,在阿育吠陀中,口服和鼻内途径是最优选的给药途径。不同的研究表明,它具有多种药理活性,包括神经保护活性、恢复活力活性、心血管活性、镇痛活性、抗炎活性、抗不育活性、抗氧化活性、自由基清除活性、抗关节炎活性等。主要从种子中提取的油用于刺激智力,增强记忆力和治疗所有年龄段的大脑相关疾病。据报道,它也是一种潜在的神经滋补剂、恢复活力剂和抗抑郁剂。野芹是我国药用植物之一,也是一种具有重要药用价值的本土药用植物。种子中含有类固醇生物碱和明亮的天然色素,其中重要的生物碱有塞拉帕氨酸、塞拉帕氨酸、塞拉帕氨酸、celapagine、celastrine和paniculatin。
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