Antimicrobial Activities of the Leaf Extracts of Ficus sycomorus Linn. on Helicobacter pylori and Citrobacter freundii

Asian Journal of Cell Biology Pub Date : 2022-08-25 DOI:10.9734/ajob/2022/v15i330240

J. Ihuma, A. Z. Koggie, T. Famojuro, L. O. Ugboji, T. D. Malgwi

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引用次数: 1

Abstract

Aims: The aim of this study is to determine the antimicrobial activities of Ficus sycomorus leave extract on selected bacteria. Phytochemical screening showed the presence of tannins, saponins, alkaloids and flavonoids, it also revealed the absence of glycoside. Place and Duration of Study: Microbiology laboratory, Biological Sciences Department, Bingham University Karu, Nasarawa State, Nigeria. Methodology: Plant extracts were prepared by boiling, soaking and methanol extraction. 96-well plates dilution method for determination of Minimum Inhibition Concentraction (MIC) and Minimum Bactericidal Concentration (MBC) were carried out. Results: The MBC for Helicobacter pylori and Citrobacter freundii showed antimicrobial activities at 400 µl each. The plant has exhibited strong antimicrobial activity on Helicobacter pylori and Citrobacter freundii. Conclusion: The antimicrobial compounds produced by plant extracts are active against bacteria. It is expected that plant extracts showing target sites other than those used by antibiotics will be active against drug-resistant microorganisms.

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梧桐叶提取物的抗菌活性研究。幽门螺杆菌和弗氏柠檬酸杆菌

目的:研究榕树叶提取物对细菌的抑菌活性。经植物化学筛选，发现其含有单宁、皂苷、生物碱和黄酮类化合物，不含糖苷。学习地点和时间:尼日利亚纳萨拉瓦州卡鲁宾汉姆大学生物科学系微生物实验室。方法:采用煮沸、浸泡、甲醇提取等方法制备植物提取物。采用96孔板稀释法测定最小抑菌浓度(MIC)和最小杀菌浓度(MBC)。结果:MBC对幽门螺杆菌和弗氏柠檬酸杆菌的抑菌活性均为400µl。该植物对幽门螺杆菌和弗氏柠檬酸杆菌具有较强的抑菌活性。结论:植物提取物制备的抗菌化合物具有抑菌活性。预计显示抗生素使用的靶点以外的植物提取物将对耐药微生物有活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Asian Journal of Cell Biology

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