p-Hydroxybenzoic Acid and Kaempferol from Desmodium triquetrum

Abstract

Desmodium triquetrum (Fabaceae) is widely distributed in Indonesia and used as herbal medicines for diuretic, hemorrhoids, tonics, and anti-inflammatory. Two known compounds, p-hydroxybenzoic acid (1) and kaempferol (2), were isolated from the MeOH extract of the leaves of Desmodium triquetrum. The structures of isolated compounds were determined based on H and C NMR data. The MeOH extract showed very active with 6,5 μg/mL in addition, compound (1) and (2) showed weak cytotoxicity against murine cell leukemia P-388 with IC50 55,0 and 24,7 μg/mL, respectively. Compound (1) was the first reported in this species.