The substantiation of the composition of a medical pencil for the prevention and treatment of diseases of the skin and the red border of the lips

T. Nesteruk, N. Polovko
{"title":"The substantiation of the composition of a medical pencil for the prevention and treatment of diseases of the skin and the red border of the lips","authors":"T. Nesteruk, N. Polovko","doi":"10.24959/nphj.22.95","DOIUrl":null,"url":null,"abstract":"Aim. To substantiate the composition of the product for the prevention and treatment of diseases of the skin and the red border of the lips in the form of a medical pencil.\nMaterials and methods. When developing the composition of a medical pencil the study objects were samples containing corn oil or the oil extract from a mixture of the medicinal plant raw material, cocoa butter, such waxes as beeswax, carnauba, candelilla, and lanolin, paraffin in various ratios, as well as the mango extract. The medical pencilcomposition was substantiated based on the results of determining the organoleptic, sensory (consumer) and physicochemical properties (melting point, hardness, spreadability and adhesion (stickiness) of the smear).\nResults and discussion. The results of the study shown that the hardness and melting point of pencils increased with an increase in the content of sealants, primarily beeswax and carnauba wax, and paraffin. An increase in the content of these components reduced the spreadability and adhesion of the base. Cocoa butter and lanonin in thecomposition of the base improved the adhesion and spreadability of the pencil, but did not provide the necessary hardness of the product. Based on the results of the study of physico-chemical and consumer properties, the bases, which included the mango extract and the oil extract from a mixture of the medicinal plant raw material (sage leaves,eucalyptus leaves, marigold flowers, chamomile flowers), were chosen. It was shown that the introduction of extracts slightly increased the melting point and hardness of the base and reduced the spreadability of the pencil.\nСonclusions. Based on the results of studying the melting point, hardness, spreadability and adhesion the composition of the wax-fat base has been chosen. The effect of the oil extract of a mixture of the medicinal plant raw material and the mango extract on the properties of the pencil base has been determined. According to the results of our research, the composition of a medical pencil for the prevention and treatment of infectious and inflammatory diseases of the skin and the red border of the lips has been proposed. It contains cocoa butter – 10 %, beeswax – 10 %, lanolin – 5 %, carnauba wax – 3 %, candelilla wax – 7 %, the mango extract – 5 % and the oil extract of a mixture of the medicinal plant raw material – up to 100.0.","PeriodicalId":19221,"journal":{"name":"News of Pharmacy","volume":"31 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"News of Pharmacy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24959/nphj.22.95","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Aim. To substantiate the composition of the product for the prevention and treatment of diseases of the skin and the red border of the lips in the form of a medical pencil. Materials and methods. When developing the composition of a medical pencil the study objects were samples containing corn oil or the oil extract from a mixture of the medicinal plant raw material, cocoa butter, such waxes as beeswax, carnauba, candelilla, and lanolin, paraffin in various ratios, as well as the mango extract. The medical pencilcomposition was substantiated based on the results of determining the organoleptic, sensory (consumer) and physicochemical properties (melting point, hardness, spreadability and adhesion (stickiness) of the smear). Results and discussion. The results of the study shown that the hardness and melting point of pencils increased with an increase in the content of sealants, primarily beeswax and carnauba wax, and paraffin. An increase in the content of these components reduced the spreadability and adhesion of the base. Cocoa butter and lanonin in thecomposition of the base improved the adhesion and spreadability of the pencil, but did not provide the necessary hardness of the product. Based on the results of the study of physico-chemical and consumer properties, the bases, which included the mango extract and the oil extract from a mixture of the medicinal plant raw material (sage leaves,eucalyptus leaves, marigold flowers, chamomile flowers), were chosen. It was shown that the introduction of extracts slightly increased the melting point and hardness of the base and reduced the spreadability of the pencil. Сonclusions. Based on the results of studying the melting point, hardness, spreadability and adhesion the composition of the wax-fat base has been chosen. The effect of the oil extract of a mixture of the medicinal plant raw material and the mango extract on the properties of the pencil base has been determined. According to the results of our research, the composition of a medical pencil for the prevention and treatment of infectious and inflammatory diseases of the skin and the red border of the lips has been proposed. It contains cocoa butter – 10 %, beeswax – 10 %, lanolin – 5 %, carnauba wax – 3 %, candelilla wax – 7 %, the mango extract – 5 % and the oil extract of a mixture of the medicinal plant raw material – up to 100.0.
一种用于预防和治疗皮肤疾病和唇红边的医用铅笔的组合物的确证
的目标。以医疗铅笔的形式证实该产品的成分,用于预防和治疗皮肤疾病和嘴唇的红边。材料和方法。在研制医用铅笔的成分时,研究对象是含有玉米油或药用植物原料、可可脂、蜂蜡、巴西棕榈、小烛花、羊毛脂、石蜡等各种比例的蜡的混合物的油提取物以及芒果提取物的样品。根据测定药膏的感官、感官(消费者)和理化性质(熔点、硬度、涂抹性和粘附性)的结果,确定了医用铅笔的成分。结果和讨论。研究结果表明,铅笔的硬度和熔点随着密封剂(主要是蜂蜡、巴西棕榈蜡和石蜡)含量的增加而增加。这些成分含量的增加会降低基材的涂抹性和附着力。可可脂和羊毛蛋白的基础成分提高了铅笔的附着力和涂抹性,但没有提供必要的产品硬度。根据理化性质和消费特性的研究结果,选择了包括芒果提取物和药用植物原料(鼠尾草叶、桉树叶、万寿菊花、洋甘菊花)混合物的油提取物的基础。结果表明,提取物的加入使基体的熔点和硬度略有提高,但降低了pencil.Сonclusions的涂抹性。通过对蜡脂基的熔点、硬度、涂覆性和附着力的研究,确定了蜡脂基的组成。测定了药用植物原料和芒果提取物的混合物的油提取物对铅笔底座性能的影响。根据我们的研究结果,提出了一种用于预防和治疗皮肤和嘴唇红边感染性和炎症性疾病的医用铅笔的成分。它含有10%的可可脂、10%的蜂蜡、5%的羊毛脂、3%的巴西棕榈蜡、7%的小烛花蜡、5%的芒果提取物和高达100.0%的药用植物原料混合物的油提取物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信