In vitro cytotoxicity of cerium dioxide nanoparticles and its effect on nitrite-ion production in normal and transplantable cell lines

Abstract

In the research, we were used normal cells that were received ex vivo, and transfected cell lines to establish the toxicity of non-stabilized and citrate-stabilized nanoparticles of cerium dioxide and to study their influence on the nitrite ion production. As a result, there was established the most effective concentrations of different type cerium dioxide nanoparticles and was showed the different response of normal and tumor cell lines.