Enflamatuar bir belirteç olan monosit – HDL oranının sigara içme durumu ile ilişkisi

Abstract

Objective: It has been shown that the monocyte/HDL ratio may be a new marker of inflammation and oxidative stress. In this study, it was aimed to investigate the monocyte / HDL ratio levels and related factors of smokers and non-smokers. Method: 84 people between the ages of 18-65 who applied to the Family Medicine Clinic of Kütahya SBÜ Evliya Çelebi Training and Research Hospital for 3 months as of December 2019 were included in the study. A questionnaire form consisting of the a personal and clinical information form consisting of 13 questions and Fagerström Nicotine Dependence Test were used as data collection tools. In addition, HDL cholesterol and complete blood count in hemogram were performed from blood samples taken from the patients. Chi-square, Mann Whitney U and Spearman correlation tests were used to analyze the data. Statistical significance value was accepted as p <0.05. Results: In this study, there was no statistically significant difference between smoking and non-smoking groups in terms of age groups, gender, chronic disease and regular medication use (p>0.05). Of the smoking participants 13.1% (n=11) were in the high addiction group, and 4.8% (n=4) in the very high addiction group according to the FNBT scale. The mean erythrocyte (p <0.001), hemoglobin (p=0.015), hematocrit (p=0.005), monocyte (p <0.001), HDL (p=0.005), MNO (p <0.001) in smoking patients were significantly higher than non-smoking patients. Conclusion: Monocyte / HDL ratio can be used as a simple, easy and cost-effective marker that can be used to predict inflammation and endothelial dysfunction in smokers.