NiFe 2O 4@Sio 2 nPr@Glucose Amine Nanoparticles as a Green and Magnetically Separable Catalyst for the Grinding Synthesis of Aryl Naphtho[1,3]Oxazine-2-Thiones

Abstract

Glucose amine‐functionalized silica‐coated NiFe2O4 nanoparticles (NiFe2O4@Sio2nPr@glucose amine) were synthesized and characterized by transmission electron microscope (TEM), Field emission scanning electron microscope (FE-SEM), fourier transform infrared spectroscopy (FT-IR), vibrating sample magnetometry (VSM), X-ray powder diffraction (XRD) and X-ray spectroscopy (EDX).  NiFe2O4@SiO2nPr@glucose amine supply an eco-friendly procedure for the synthesis of 1,3-oxazine-2-thiones through three-component grinding reaction of various aldehydes, thiourea, and α-naphthol or β-naphthol in accordance with green chemistry rules. These compounds were obtained in high yields and short reaction times. The catalyst could be easily recovered and reused for six cycles with almost consistent activity. The structures of the synthesized Aryl naphtho[1,3]oxazine-2-thione compounds were confirmed by 1H NMR, 13C NMR and FTIR spectral data and elemental analyses.