2.2.2. Synthesis, crystal structure and biological activity of triphenyltin 4-acetylphenolate

Zhikun Liua, Yunsai Donga, X. Zhengb, You Yua, Laijin Tiana
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Abstract

Abs t ract : Tr i ph en yl t in 4-a cet yl ph en ol at e, 4- CH 3 COC 6 H 4 OSnPh 3 (1), has been synthesized and characterized by elemental analysis, IR, NMR ( 1 H, 13 C and 119 Sn) spectra, and X-ray single crystal diffraction. Compound  1 possesses a trans-C 3 SnO 2 trigonal bipyramidal geometry with the axial positions occupied by the phenolate oxygen and carbonyl oxygen of an adjacent molecule and form an one-dimensional infinite chain. Bioassay results have shown that the compound has good in vitro anti-bacterial and anti-tumor activities. Supporting information: X-Ray (CIF file)
2.2.2. 乙酰酚酸三苯基锡的合成、晶体结构及生物活性
合成了一种新的合成物:Tr i ph en yl t in 4-a - et yl ph en ol at e, 4- CH 3 COC 6 h4 osnph3(1),并通过元素分析、IR、NMR (1h、13c和119sn)光谱和x射线单晶衍射对其进行了表征。化合物1具有反式c3sno2的三角双锥体结构,其轴向位置由相邻分子的酚氧和羰基氧占据,形成一维无限链。生物实验结果表明,该化合物具有良好的体外抗菌和抗肿瘤活性。支持信息:x射线(CIF文件)
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