Effects of meteorological parameters on antimicrobial activity of penicillium species in hospital environment

Anima Nanda, S. Akila
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引用次数: 0

Abstract

The atmospheric fungal spores are an ever-present component and well known particulate matter to trigger asthma and hay fever symptoms in atopic individuals. The hospital atmosphere near Chennai central, Chennai, Tamilnadu has been monitored for airborne fungal spores at several sampling stations by Petri-plate settlement method. In qualitative and quantitative way, fungal spores considerably varied from season to season. The proposed study involved the examination of the antimicrobial activity of Penicillium spp and correlated with meteorological data recorded during the study period. The bioactive compounds of Penicillium spp of hospital environment at different sites of different seasons were extracted and then subjected for its antimicrobial activity study with different bacterial pathogens. The activity was also compared using different antibiotic discs (Tetracycline, Vancomycin, Ampicillin, Amoxicillin and Penicillin-G). The Penicillium spp isolated from hospital environment during winter season showed good activity against the pathogens than the other seasons.
气象参数对医院环境中青霉菌抗菌活性的影响
大气真菌孢子是一种普遍存在的成分和众所周知的颗粒物质,可引发特应性个体的哮喘和花粉热症状。在泰米尔纳德邦金奈市金奈中心附近的几个采样站,用培养皿沉降法监测了空气中的真菌孢子。在定性和定量方面,真菌孢子随季节变化很大。拟议的研究包括对青霉菌抗菌活性的检查,并与研究期间记录的气象数据相关联。提取不同季节不同地点医院环境中青霉属的生物活性化合物,对不同病原菌进行抑菌活性研究。并比较了不同抗生素盘(四环素、万古霉素、氨苄西林、阿莫西林和青霉素- g)的活性。冬季从医院环境中分离得到的青霉菌对病原菌的抑制作用较好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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