Some biochemical effects of thiouracil on the response of the immature pullet to estrogen.

Abstract

Thiouracil depressed the increases of serum calcium, serum riboflavin, and serum vitamin A evoked by estrogen in the sexually immature pullet. In these respects the effects of thiouracil resembled the effects of thyroxine. In contrast to thyroxine, however, thiouracil increased the hypertrophy of the liver and oviduct induced by estrogen. Estrogen did not significantly increase total liver riboflavin, whereas estrogen plus thiouracil produced a significant increase.