Mid-Borderline Leprosy with Mild Type 1 Reaction in Children: A Case Report

Anindia Indraswari, M. Listiawan
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Abstract

Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Cases of leprosy in children are rarely found because of the long incubation period of Mycobacterium leprae. Purpose: To report a case of mid-borderline leprosy with a mild type 1 reaction in a seven-years-old girl patient. Case: A 7-years-old girl patient presented with multiple red and white patches on her face, body, arms, legs, and buttocks since 6 months before. There was no itching, numbness, painr fever. There was no thickening of peripheral nerves and no nerve function impairment. Her grandmother was suspected to have leprosy, but she had never been treated and had already passed away. From the acid fast bacilli (AFB) examination, the bacterial index (BI) was 1+ and the morphological index (MI) was 2%. A serologic test examination was also performed and the result were Immunoglobulin (Ig) G  3716 u/ml and IgG 284 u/ml. The patient got multidrugs therapy for 12 months and after 9 months of treatment, the pre-existing patches became erythematous, thickened, and felt pain when touched, but there was no fever. In the presence of pain, oral ibuprofen was then administered and the patches began to improveDiscussion: Due to the possibility of leprosy reaction, it is important to immediately give prompt treatment to children with type 1 leprosy reaction that is associated with neuritis and leads to deformities. Conclusion: Early diagnosis and therapy for a type 1 leprosy reaction are very important to prevent deformities.
轻度1型反应的儿童中边缘性麻风病1例报告
背景:麻风是一种由麻风分枝杆菌引起的慢性传染病。由于麻风分枝杆菌潜伏期长,很少发现儿童麻风病例。目的:报告一例轻度1型反应的7岁女孩中边缘性麻风病。病例:7岁女童患者,6个月前出现面部、身体、手臂、腿部、臀部多发红白斑块。没有瘙痒,麻木,疼痛,发烧。无周围神经增厚,无神经功能损伤。她的祖母被怀疑患有麻风病,但她从未接受过治疗,已经去世了。抗酸杆菌(AFB)检查,细菌指数(BI)为1+,形态指数(MI)为2%。同时进行血清学检查,免疫球蛋白G 3716 u/ml, IgG 284 u/ml。患者多药治疗12个月,治疗9个月后,原有斑块出现红斑、增厚、触摸疼痛,但无发热。讨论:由于麻风病反应的可能性,对伴有神经炎并导致畸形的1型麻风病反应的儿童立即给予及时治疗是很重要的。结论:1型麻风反应的早期诊断和治疗对预防畸形具有重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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