PENGARUH VARIASI KONSENTRASI GELLING AGENT HPMC (Hidroxypropyl methylcellulose) TERHADAP SIFAT FISIK GEL EKSTRAK ETANOL BIJI EDAMAME (Glycine max)

JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Pub Date : 2022-12-20 DOI:10.53864/jifakfar.v3i2.150

Dewi - Rashati, Icha Ayuning Suprayitno

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Abstract

Edamame seeds (glycine max (L) merr) is a soybean variety that is harvested while still young. Isoflavones present in soybeans such as deidzein, glycitein, and genistein have activity in inhibiting the tyrosinase enzyme to achieve skin lightening effects for skin whitening cosmetics. In this study the gel was formulated with HPMC (Hydroxypropyl methylcellulose) 2%, 3%, 5% as a gel forming agent. Evaluation includes organoleptic, homogeneity, pH, viscosity, and spreadability. The results of organoleptic evaluation of gel form in formula 1 fulfill the requirements, in formula 2 and 3 do not meet the requirements. The physical properties of the odor and color organoleptic formulas 1, 2, and 3 are eligible. in the homogeneity test of formulas 1, 2, and 3 are homogen. In the pH test formula 1,2,3 fulfills skin pH susceptibility pH 6. In the viscosity test of formula 1 250 dPa.S, Formula 2 500 dPa.S and formula 3 800 dPa.S.in the spread test of formula 1 it is 4.4cm, formula 2 is 3.8cm, and formula 3 is 3.7cm. From the results test of the Formula 1 (2% HPMC) meets all physical requirements of the gels.

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毛豆种子(glycine max (L) merr)是一种大豆品种，在还年轻的时候就收获了。大豆中存在的异黄酮如去黄素、糖苷、染料木素等具有抑制酪氨酸酶的活性，从而达到美白化妆品的亮肤效果。在本研究中，以HPMC(羟丙基甲基纤维素)2%，3%，5%作为凝胶形成剂配制凝胶。评价包括感官、均匀性、pH值、粘度和铺展性。公式1中凝胶形态的感官评价结果满足要求，公式2和公式3不满足要求。气味和颜色感官公式1、2和3的物理性质是合格的。在同质性检验中，公式1、2、3是同质的。pH试验中公式1、2、3满足皮肤pH敏感性pH值6。在粘度试验中，公式1为250dpa。S，公式2500dpa。公式1的扩散试验为4.4cm，公式2为3.8cm，公式3为3.7cm。从试验结果来看，公式1 (2% HPMC)满足了凝胶的所有物理要求。

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JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER

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