Asymptomatic Bacteriuria in Relation to Diabetic Women Attending Hawassa University Referral Hospital, Southern Ethiopia

Bulti Kumera, T. Anteneh, K. Aragaw
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引用次数: 2

Abstract

The aim of the current study was to investigate the association between diabetes and ASB in women, identify the bacteria involved and determine their antimicrobial resistance. Diabetic (n=100) and non-diabetic (n=100) nonpregnant women, with no abnormalities of the urinary tract were involved in the study. Clean-catch midstream urine samples were collected for bacterial isolation and identification. Questionnaire was used to collect demographic and clinical information of the patient. ASB was diagnosed in 22(22%) diabetic and 15(15%) nondiabetic women. Escherichia coli, Staphylococcus aureus, coagulase negative staphylococci, Klebsiella pneumoniae and Proteus species were isolated from both groups of study subjects. There was no statistically significant difference in the relative frequency of isolated bacteria species among the two groups of patients (P>0.05). Most of the isolated bacteria were resistant to amoxicillin (96%), penicillin (92%) and vancomycin (70%), but susceptible to ceftriaxone (60%), norfloxacin (62%) and gentamicin (62%). Occurrence of ASB was not associated with diabetic status in women attending Hawassa University Referral Teaching Hospital.
埃塞俄比亚南部阿瓦萨大学转诊医院糖尿病妇女的无症状菌尿
当前研究的目的是调查糖尿病和女性ASB之间的关系,确定所涉及的细菌并确定其抗菌素耐药性。研究对象为糖尿病(n=100)和非糖尿病(n=100)未怀孕且无尿路异常的妇女。采集中游清洁尿液样本进行细菌分离鉴定。采用调查问卷收集患者的人口学和临床资料。22名(22%)糖尿病女性和15名(15%)非糖尿病女性被诊断为ASB。两组研究对象均分离出大肠杆菌、金黄色葡萄球菌、凝固酶阴性葡萄球菌、肺炎克雷伯菌和变形杆菌。两组患者分离菌种相对频率比较,差异无统计学意义(P>0.05)。大多数分离菌对阿莫西林(96%)、青霉素(92%)和万古霉素(70%)耐药,但对头孢曲松(60%)、诺氟沙星(62%)和庆大霉素(62%)敏感。在Hawassa大学转诊教学医院就诊的女性中,ASB的发生与糖尿病状态无关。
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